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公开(公告)号:US20100310555A1
公开(公告)日:2010-12-09
申请号:US12611397
申请日:2009-11-03
IPC分类号: A61K39/395 , A61K38/17 , A61K31/713 , A61P3/10 , A61P17/06 , A61P19/02 , A61P27/02 , A61P29/00 , A61P31/12 , A61P35/02
CPC分类号: A61K39/3955 , A61K38/02 , A61K38/1866 , A61K38/1891 , C12N5/0669
摘要: The present invention provides methods of using Bv8 and EG-VEGF polypeptides and nucleic acids to promote hematopoiesis. Also provided herein are methods of screening for modulators of Bv8 and EG-VEGF activity. Furthermore, methods of treatment using Bv8 and EG-VEGF polypeptides or Bv8 and EG-VEGF antagonists are provided.
摘要翻译: 本发明提供使用Bv8和EG-VEGF多肽和核酸促进造血作用的方法。 本文还提供筛选Bv8和EG-VEGF活性调节剂的方法。 此外,提供了使用Bv8和EG-VEGF多肽或Bv8和EG-VEGF拮抗剂的治疗方法。