Abstract:
A PROCESS FOR THE PRODUCTION OF A POLYMER HAVING DIHALO-S-TRIAZINYL GROUPS BOUND THERETO WHICH COMPRISES CONTACTING A POLYMER HAVING NUCLEOPHILIC GROUPS WITH A SOLUTION OF A CYANURIC HALIDE IN AN INERT WATER-MISCIBLE ORGANIC SOLVENT IN THE PRESENCE OF WATER AND MAINTAINING AN ACID OR NEUTRAL PH AFTER REACTION HAS OCCURED WHEREBY THE TENDENCY TO HYDROLYSIS AND CROSS-LINKING OF THE POLYMER IS SUBSTANTIALLY REDUCED.
Abstract:
A polymer that is substituted by pendant triazinyl groups of the formula:
WHERE X represents a radical capable of reacting with a biologically active substance, and Y represents a halogen atom, or a nucleophilic group that is an amino group, or an aliphatic or aromatic group, and also by a further substituent group which has a positive charge when the polymer is in contact with a solution having a pH in the normal biological range.
Abstract:
A polymeric matrix having a biologically active substance chemically bound thereto, which comprises a polymer and a biologically active substance linked by groups of the formula:
WHERE Y represents a nucleophilic substituent that is an amino group, or an aliphatic or aromatic group.