公开(公告)号：US20150352187A1

公开(公告)日：2015-12-10

申请号：US14654624

申请日：2013-12-24

申请人： NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY

发明人： Akihito YAMAMOTO ,  Minoru UEDA ,  Kohki MATSUBARA ,  Akio SUZUMURA ,  Koichi FURUKAWA ,  Yoshihiro MATSUSHITA ,  Hirotaka WAKAYAMA ,  Nobunori TAKAHASHI ,  Shin TSUNEKAWA ,  Takako IZUMOTO

IPC分类号： A61K38/19 ,  C12N5/0786 ,  A61K31/737 ,  A61K45/06 ,  A61K38/17

CPC分类号： A61K38/195 ,  A61K31/737 ,  A61K38/178 ,  A61K45/06 ,  C12N5/0645 ,  C12N2501/21 ,  C12N2501/59 ,  C12N2501/90 ,  A61K2300/00

摘要： A composition having tissue repair activity, which is capable of promoting reactions associated with tissue repair, contains at least one selected from the group consisting of a first component that is a protein having a monocyte chemotactic protein-1 (MCP-1) activity, a second component that is a protein having the extracellular domain activity of sialic acid-binding immunoglobulin-type lectin-9 (Siglec-9), and a third component that is at least one of chondroitin sulfate and chondroitin sulfate proteoglycan.

摘要翻译： 具有能够促进与组织修复相关的反应的组织修复活性的组合物含有选自由具有单核细胞趋化蛋白-1（MCP-1）活性的蛋白质组成的组中的至少一种， 第二组分，其是具有唾液酸结合免疫球蛋白型凝集素-9（Siglec-9）的细胞外结构域活性的蛋白质，以及作为硫酸软骨素和硫酸软骨素蛋白多糖中的至少一种的第三成分。