专利检索 ap:("NATIONAL UNIVERSITY OF SINGAPORE" OR "UNIVERSITY OF MYSORE" OR "BANGALORE UNIVERSITY") AND inv:"Rangappa Kanchugarakoppal Subbegowda" 第 1 页

1.

发明授权
Compounds useful in inhibiting human trefoil factor 3 有权

公开(公告)号：US11141402B2

公开(公告)日：2021-10-12

申请号：US16619218

申请日：2018-06-05

申请人： NATIONAL UNIVERSITY OF SINGAPORE , UNIVERSITY OF MYSORE , BANGALORE UNIVERSITY

发明人： Peter Edward Lobie , Vijay Kumar Pandey , Rangappa Kanchugarakoppal Subbegowda , Basappa , Mohan Chakrabhavi Dhananjaya , Shobith Rangappa

IPC分类号： A61K31/37 , A61K31/4433 , A61K45/06 , C07D493/04

摘要： Disclosed herein are compounds of Formula I, wherein A, R1 to R6, and x to z have the meanings given in the description.

2.

发明授权
Small molecule inhibitors of BCL-2-associated death promoter (BAD) phosphorylation 有权

公开(公告)号：US11292773B2

公开(公告)日：2022-04-05

申请号：US16605630

申请日：2018-04-18

申请人： NATIONAL UNIVERSITY OF SINGAPORE , UNIVERSITY OF MYSORE , BANGALORE UNIVERSITY

发明人： Peter Edward Lobie , Vijay Kumar Pandey , Rangappa Kanchugarakoppal Subbegowda , Bassappa Salundi , Mohan Chakrabhavi Dhananjaya , Shobith Rangappa , Srinivasa Venkatachalaiah

IPC分类号： C07D241/04 , A61P35/00 , C07D405/06 , C07D409/06 , C07D413/04 , C07D471/06 , C07D213/53 , C07D295/096 , C07D295/155 , C07D295/192 , C07D307/52 , C07D333/20 , A61K31/495 , A61K31/496

摘要： The invention relates to compounds of general formula (I): wherein R1, n, R2a, R2b, and R3 are as defined herein. The compounds are inhibitors of Bcl-2-associated death promoter (BAD) phosphorylation and have anti-apoptotic activity and are useful in the treatment of cancer, particularly breast cancer, endometrial cancer, ovarian cancer, liver cancer, colon cancer, prostate cancer or pancreatic cancer.