公开(公告)号：US20160367494A1

公开(公告)日：2016-12-22

申请号：US15185657

申请日：2016-06-17

Applicant: NITTO DENKO CORPORATION

Inventor： Yu TACHIKAWA ,  Satoshi AMEYAMA ,  Eriko ABE ,  Tetsuya NAKAMURA ,  Naoko URUSHIHARA ,  Jun ISHIKURA ,  Kazuhiro AOYAGI ,  Yoshitaka INOUE ,  Akira YOKOUCHI ,  Tomoya TANAKA

IPC: A61K9/70 ,  A61K31/27 ,  A61K31/428 ,  A61K31/137 ,  A61K47/14

CPC classification number: A61K9/7061 ,  A61K31/137 ,  A61K31/27 ,  A61K31/428 ,  A61K47/14 ,  A61L15/44 ,  A61L15/58 ,  C08L33/06

Abstract: A patch preparation includes a support and a pressure-sensitive adhesive layer formed on one surface of the support. The pressure-sensitive adhesive layer includes: (A) a polymer prepared by copolymerizing monomer components including a hydroxyl group-containing monomer and an alkyl (meth)acrylate monomer; (B) a polymer prepared by copolymerizing monomer components including a methyl methacrylate monomer and a butyl methacrylate monomer; and (C) a basic drug, provided that bisoprolol and a salt thereof are excluded.

Abstract translation: 贴片制剂包括支撑体和形成在支撑体的一个表面上的压敏粘合剂层。 压敏粘合剂层包括：（A）通过使包含含羟基的单体和（甲基）丙烯酸烷基酯单体的单体成分共聚而制备的聚合物; （B）通过使包含甲基丙烯酸甲酯单体和甲基丙烯酸丁酯单体的单体组分共聚制备的聚合物; 和（C）碱性药物，条件是排除比索洛尔及其盐。