公开(公告)号：US20130165876A1

公开(公告)日：2013-06-27

申请号：US13726753

申请日：2012-12-26

Applicant: Nitto Denko Corporation

Inventor： Kazuhiro AOYAGI ,  Yoshihiro IWAO ,  Kensuke MATSUOKA ,  Tomoya TANAKA

IPC: A61K9/70

CPC classification number: A61K9/7038 ,  A61F13/0259 ,  A61F2013/00646 ,  A61K9/703 ,  A61K9/7053 ,  A61K9/7076

Abstract: The present invention relates to a patch preparation having a central part and a peripheral part surrounding the central part, the patch preparation comprising: a patch preparation main body having a support and an adhesive layer which contains a drug and is formed on the support; and a release liner laminated on the adhesive layer, wherein the peripheral part has a predetermined area, and a peel force between the adhesive layer and the release liner in the predetermined area is greater than a peel force between the adhesive layer and a release liner in the central part.

Abstract translation: 本发明涉及一种具有中心部分和围绕中心部分的周边部分的贴片制剂，所述贴片制剂包括：贴片制剂主体，其具有支撑体和粘合剂层，所述粘合剂层含有药物并形成在所述载体上; 以及层叠在粘合剂层上的剥离衬垫，其中周边部分具有预定区域，并且在预定区域中粘合剂层和剥离衬垫之间的剥离力大于粘合剂层和剥离衬垫之间的剥离力 中心部分。

公开(公告)号：US20190231712A1

公开(公告)日：2019-08-01

申请号：US16262391

申请日：2019-01-30

Applicant: NITTO DENKO CORPORATION

Inventor： Chie MATSUMOTO ,  Tomohito TAKITA ,  Kaiji FUJIWARA ,  Akinori SUGIYAMA ,  Tomoya TANAKA

IPC: A61K9/70 ,  A61K47/12 ,  A61K47/18 ,  A61K31/197 ,  A61K47/32 ,  A61K47/38 ,  A61K47/36

CPC classification number: A61K9/7084 ,  A61K9/7023 ,  A61K31/197 ,  A61K47/12 ,  A61K47/18 ,  A61K47/32 ,  A61K47/36 ,  A61K47/38

Abstract: Provided is a transdermal absorption preparation having superior drug skin permeability, which can uniformly disperse the drug in the preparation and maintain the uniform dispersion state of the drug.A transdermal absorption preparation having a plaster layer containing a drug, a polymer and a pH adjuster, in which the aforementioned polymer contains a polymer having a particular glass transition temperature of 30° C.-200° C., and the surface of the plaster layer has a pH of 6.7-10.0.

公开(公告)号：US20160367494A1

公开(公告)日：2016-12-22

申请号：US15185657

申请日：2016-06-17

Applicant: NITTO DENKO CORPORATION

Inventor： Yu TACHIKAWA ,  Satoshi AMEYAMA ,  Eriko ABE ,  Tetsuya NAKAMURA ,  Naoko URUSHIHARA ,  Jun ISHIKURA ,  Kazuhiro AOYAGI ,  Yoshitaka INOUE ,  Akira YOKOUCHI ,  Tomoya TANAKA

IPC: A61K9/70 ,  A61K31/27 ,  A61K31/428 ,  A61K31/137 ,  A61K47/14

CPC classification number: A61K9/7061 ,  A61K31/137 ,  A61K31/27 ,  A61K31/428 ,  A61K47/14 ,  A61L15/44 ,  A61L15/58 ,  C08L33/06

Abstract: A patch preparation includes a support and a pressure-sensitive adhesive layer formed on one surface of the support. The pressure-sensitive adhesive layer includes: (A) a polymer prepared by copolymerizing monomer components including a hydroxyl group-containing monomer and an alkyl (meth)acrylate monomer; (B) a polymer prepared by copolymerizing monomer components including a methyl methacrylate monomer and a butyl methacrylate monomer; and (C) a basic drug, provided that bisoprolol and a salt thereof are excluded.

Abstract translation: 贴片制剂包括支撑体和形成在支撑体的一个表面上的压敏粘合剂层。 压敏粘合剂层包括：（A）通过使包含含羟基的单体和（甲基）丙烯酸烷基酯单体的单体成分共聚而制备的聚合物; （B）通过使包含甲基丙烯酸甲酯单体和甲基丙烯酸丁酯单体的单体组分共聚制备的聚合物; 和（C）碱性药物，条件是排除比索洛尔及其盐。