公开(公告)号：US20170082570A1

公开(公告)日：2017-03-23

申请号：US15267683

申请日：2016-09-16

申请人： NLT TECHNOLOGIES, LTD.

发明人： Kazushige TAKECHI ,  Shinnosuke IWAMATSU ,  Yutaka ABE ,  Toru YAHAGI ,  Shunsuke KONNO ,  Mutsuto KATOH

IPC分类号： G01N27/327 ,  C12Q1/00

CPC分类号： C12Q1/006 ,  C12Q1/002 ,  G01N27/4145 ,  G01N2333/90206

摘要： A TFT biosensor includes a gate electrode (silicon substrate), a reference electrode, and enzyme that is fixed to an insulating substrate spatially separated from the gate electrode and the reference electrode. A pH variation in the vicinity of an ion-sensitive insulating film is induced by a reaction between the enzyme and a sensing object material. The TFT biosensor can detect a concentration of the sensing object material with high sensitivity by detecting the pH variation as a threshold voltage shift of characteristics of a gate-source voltage to a source-drain current.