公开(公告)号：US20230117773A1

公开(公告)日：2023-04-20

申请号：US17937866

申请日：2022-10-04

Applicant: NOBLIS, INC.

Inventor： Shane MITCHELL ,  Sterling Thomas ,  Masooda Omari ,  Tyler W. Barrus ,  Mychal Ivancich

IPC: C12Q1/6851 ,  C12Q1/6806 ,  C12Q1/6811 ,  C12Q1/6825 ,  C12Q1/6855 ,  G16B30/00

Abstract: Portable biosurveillance kits for sequencing and sample identification are provided, and techniques for configuring said kits are provided. A system for configuring a kit may receive data representing a first and second set of nucleic acid sequences, and may generate and store first and second indexes representing the respective sets. The system may then use the indexes to identify conserved-signature sequences that satisfy abundance criteria with respect to the first set and sparsity criteria with respect to the second set. The identified conserved-signature sequences may be stored on (or represented in storage on) a portable sequencing and sample-identification kit, which may compare the conserved-signature sequence to a sample sequence in order to identify the sample sequence.

公开(公告)号：US10560552B2

公开(公告)日：2020-02-11

申请号：US14718950

申请日：2015-05-21

Applicant: NOBLIS, INC.

Inventor： Sterling Thomas ,  Nate Dellinger ,  Mychal Ivancich

IPC: H04L29/06 ,  H03M7/30 ,  G16B30/00

Abstract: Systems and methods for performing genomic information compression, transmission, and decompression are provided. A system for compression, transmission, and decompression of genomic information includes a first computer associated with a first index and a second computer associated with a second index, each index containing reference permutations of nucleic acid sequence portions, each permutation associated with a reference number. The first computer uses input genomic information and the first index to produce a compressed representation of the genomic information, and transmits the compressed representation to the second computer. The second computer uses the compressed representation and the second index to assemble a data representation of the genomic information. The compressed representation comprises references to permutations, indications of locations of each permutation in the input information, indications of variations to permutations, and/or indications of sequence length.