公开(公告)号：US20220000118A1

公开(公告)日：2022-01-06

申请号：US16492722

申请日：2018-03-08

申请人： NORTH CAROLINA STATE UNIVERSITY ,  AGILE SCIENCES, INC.

发明人： Christian Melander ,  David Kendall Jung ,  Samuel Onofre Reyes

IPC分类号： A01N47/30 ,  C07D233/88 ,  C07D405/12 ,  C07D409/12 ,  C07D401/12 ,  C07D235/30 ,  C07D403/12 ,  A61K31/4168 ,  A61K31/5377 ,  A61K31/4178 ,  A61K31/4439 ,  A61K31/4184 ,  A01P1/00 ,  A61P31/04 ,  A01N47/36 ,  A01N47/32 ,  C09D5/14 ,  A61L2/232

摘要： Provided are 2-aminoimidazole-phenyl derivative compounds of Formula (I): which compounds are useful in methods of controlling microbial growth, such as by enhancing the effects of an antibiotic administered in combination with the compound. Compositions including these compounds, devices including these compounds, and methods of using the same are also provided.

公开(公告)号：US11582970B2

公开(公告)日：2023-02-21

申请号：US16492722

申请日：2018-03-08

申请人： NORTH CAROLINA STATE UNIVERSITY

发明人： Christian Melander ,  David Kendall Jung ,  Samuel Onofre Reyes

IPC分类号： A01N47/30 ,  A61P31/04 ,  A01P1/00 ,  A01N47/32 ,  A01N47/36 ,  A61K31/4168 ,  A61K31/4178 ,  A61K31/4184 ,  A61K31/4439 ,  A61K31/5377 ,  A61L2/232 ,  C07D233/88 ,  C07D235/30 ,  C07D401/12 ,  C07D403/12 ,  C07D405/12 ,  C07D409/12 ,  C09D5/14

摘要： Provided are 2-aminoimidazole-phenyl derivative compounds of Formula (I): which compounds are useful in methods of controlling microbial growth, such as by enhancing the effects of an antibiotic administered in combination with the compound. Compositions including these compounds, devices including these compounds, and methods of using the same are also provided.