公开(公告)号：USRE49080E1

公开(公告)日：2022-05-24

申请号：US16793734

申请日：2020-02-18

申请人： Novartis AG

发明人： Gregory Raymond Bebernitz ,  Mark G. Bock ,  Dumbala Srinivas Reddy ,  Atul Kashinath Hajare ,  Vinod Vyavahare ,  Sandeep Bhausaheb Bhosale ,  Suresh Eknath Kurhade ,  Videsh Salunkhe ,  Nadim S. Shaikh ,  Debnath Bhuniya ,  P. Venkata Palle ,  Lili Feng ,  Jessica Liang

IPC分类号： A61K31/7052 ,  A61K31/7048 ,  A61K31/706 ,  C07D405/10 ,  C07D407/10 ,  C07D413/10 ,  C07H7/04

摘要： This invention relates to compounds represented by formula (I): wherein the variables are defined as herein above, which are useful for treating diseases and conditions mediated by the sodium D-glucose co-transporter (SGLT), e.g. diabetes. The invention also provides methods of treating such diseases and conditions, and compositions etc. for their treatment.

公开(公告)号：US09895389B2

公开(公告)日：2018-02-20

申请号：US15134016

申请日：2016-04-20

申请人： Novartis AG

发明人： Gregory Raymond Bebernitz ,  Mark G. Bock ,  Dumbala Srinivas Reddy ,  Atul Kashinath Hajare ,  Vinod Vyavahare ,  Sandeep Bhausaheb Bhosale ,  Suresh Eknath Kurhade ,  Videsh Salunkhe ,  Nadim S. Shaikh ,  Debnath Bhuniya ,  P. Venkata Palle ,  Lili Feng ,  Jessica Liang

IPC分类号： A61K31/7048 ,  A61K31/706 ,  A61K31/7052 ,  C07D405/10 ,  C07D407/10 ,  C07D413/10 ,  C07H7/04

CPC分类号： A61K31/7052 ,  A61K31/7048 ,  A61K31/706 ,  C07D405/10 ,  C07D407/10 ,  C07D413/10 ,  C07H7/04

摘要： This invention relates to compounds represented by formula (I): wherein the variables are defined as herein above, which are useful for treating diseases and conditions mediated by the sodium D-glucose co-transporter (SGLT), e.g. diabetes. The invention also provides methods of treating such diseases and conditions, and compositions etc. for their treatment.

公开(公告)号：US20170042925A1

公开(公告)日：2017-02-16

申请号：US15134016

申请日：2016-04-20

申请人： NOVARTIS AG

发明人： Gregory Raymond Bebernitz ,  Mark G. Bock ,  Dumbala Srinivas Reddy ,  Atul Kashinath Hajare ,  Vinod Vyavahare ,  Sandeep Bhausaheb Bhosale ,  Suresh Eknath Kurhade ,  Videsh Salunkhe ,  Nadim S. Shaikh ,  Debnath Bhuniya ,  P. Venkata Palle ,  Lili Feng ,  Jessica Liang

IPC分类号： A61K31/7052 ,  A61K31/706

CPC分类号： A61K31/7052 ,  A61K31/7048 ,  A61K31/706 ,  C07D405/10 ,  C07D407/10 ,  C07D413/10 ,  C07H7/04

摘要： This invention relates to compounds represented by formula (I): wherein the variables are defined as herein above, which are useful for treating diseases and conditions mediated by the sodium D-glucose co-transporter (SGLT), e.g. diabetes. The invention also provides methods of treating such diseases and conditions, and compositions etc. for their treatment.

摘要翻译： 其中所述变量如上文所定义，其可用于治疗由D-葡萄糖共转运蛋白（SGLT）介导的疾病和病症，例如， 糖尿病。 本发明还提供了治疗这些疾病和病症以及组合物等的治疗方法。