公开(公告)号：US20180327486A1

公开(公告)日：2018-11-15

申请号：US15973225

申请日：2018-05-07

Applicant: NOVARTIS AG

Inventor： Leslie Ngozi Anuna JOHNSON ,  Ute JAEGER ,  Yong-In KIM ,  Christian Carsten Silvester KUNZ ,  Igor SPLAWSKI ,  Michael ROGUSKA ,  Joy GHOSH ,  Barbara BRANNETTI ,  Michael STEFANIDAKIS ,  Sha-Mei LIAO

IPC: C07K16/18 ,  C07K16/24 ,  G01N33/68 ,  A61K39/395

CPC classification number: C07K16/18 ,  A61K39/3955 ,  A61K2039/505 ,  A61K2039/507 ,  C07K16/24 ,  C07K2317/21 ,  C07K2317/30 ,  C07K2317/33 ,  C07K2317/40 ,  C07K2317/55 ,  C07K2317/565 ,  C07K2317/76 ,  C07K2317/92 ,  G01N33/6863

Abstract: The present invention relates to antibodies or antigen binding fragments thereof that bind to complement Factor P and used thereof as well as combinations of anti-Factor P antibodies with antibodies or antigen binding fragments thereof that bind to complement component 5 (C5).