公开(公告)号：US20130295102A1

公开(公告)日：2013-11-07

申请号：US13716526

申请日：2012-12-17

Applicant: Novartis AG

Inventor： Leslie Ngozi Anuna Johnson ,  Ute Jaeger ,  Yong-In Kim ,  Christian Carsten Silvester Kunz ,  Igor Splawski ,  Michael Roguska ,  Joy Ghosh ,  Barbara Brannetti

IPC: C07K16/18 ,  G01N33/68 ,  C07K16/24 ,  A61K39/395

CPC classification number: C07K16/18 ,  A61K39/3955 ,  A61K2039/505 ,  A61K2039/507 ,  C07K16/24 ,  C07K2317/21 ,  C07K2317/30 ,  C07K2317/33 ,  C07K2317/40 ,  C07K2317/55 ,  C07K2317/565 ,  C07K2317/76 ,  C07K2317/92 ,  G01N33/6863

Abstract: The present invention relates to antibodies or antigen binding fragments thereof that bind to complement Factor P and used thereof as well as combinations of anti-Factor P antibodies with antibodies or antigen binding fragments thereof that bind to complement component 5 (C5).

公开(公告)号：US09988440B2

公开(公告)日：2018-06-05

申请号：US14309330

申请日：2014-06-19

Applicant: NOVARTIS AG

Inventor： Leslie Ngozi Anuna Johnson ,  Ute Jaeger ,  Yong-In Kim ,  Christian Carsten Silvester Kunz ,  Igor Splawski ,  Michael Roguska ,  Joy Ghosh ,  Barbara Brannetti ,  Michael Stefanidakis ,  Sha-Mei Liao

IPC: A61K39/395 ,  C07K16/18 ,  G01N33/68 ,  C07K16/24 ,  A61K39/00

CPC classification number: C07K16/18 ,  A61K39/3955 ,  A61K2039/505 ,  A61K2039/507 ,  C07K16/24 ,  C07K2317/21 ,  C07K2317/30 ,  C07K2317/33 ,  C07K2317/40 ,  C07K2317/55 ,  C07K2317/565 ,  C07K2317/76 ,  C07K2317/92 ,  G01N33/6863

Abstract: The present invention relates to antibodies or antigen binding fragments thereof that bind to complement Factor P and used thereof as well as combinations of anti-Factor P antibodies with antibodies or antigen binding fragments thereof that bind to complement component 5 (C5).

公开(公告)号：US09051365B2

公开(公告)日：2015-06-09

申请号：US13716526

申请日：2012-12-17

Applicant: NOVARTIS AG

Inventor： Leslie Ngozi Anuna Johnson ,  Ute Jaeger ,  Yong-In Kim ,  Christian Carsten Silvester Kunz ,  Igor Splawski ,  Michael Roguska ,  Joy Ghosh ,  Barbara Brannetti ,  Sha-Mei Liao ,  Michael Stefanidakis

IPC: A61K39/395 ,  C07K16/28 ,  C07K16/18 ,  G01N33/68 ,  C07K16/24 ,  A61K39/00

CPC classification number: C07K16/18 ,  A61K39/3955 ,  A61K2039/505 ,  A61K2039/507 ,  C07K16/24 ,  C07K2317/21 ,  C07K2317/30 ,  C07K2317/33 ,  C07K2317/40 ,  C07K2317/55 ,  C07K2317/565 ,  C07K2317/76 ,  C07K2317/92 ,  G01N33/6863

Abstract: The present invention relates to antibodies or antigen binding fragments thereof that bind to complement Factor P and used thereof as well as combinations of anti-Factor P antibodies with antibodies or antigen binding fragments thereof that bind to complement component 5 (C5).

Abstract translation: 本发明涉及结合补体因子P并用于其的抗体或其抗原结合片段，以及抗因子P抗体与结合补体成分5（C5）的抗体或其抗原结合片段的组合。