公开(公告)号：US20180298456A1

公开(公告)日：2018-10-18

申请号：US15767551

申请日：2016-10-12

Applicant: NOVOZYMES A/S

Inventor： Shikha Gupta ,  Allan Svendsen ,  Vivek Srivastava ,  Marco Malten ,  Thomas Agersten Poulsen ,  Preethi Ramaiya ,  Beth Nelson ,  Vasudeva P. Rao ,  Padmavathi Balumuri

IPC: C12P19/02 ,  C12P19/20 ,  C12N9/34 ,  C12P19/14

Abstract: The present invention relates to glucoamylase variants having an increase in specific activity and/or an increase in melting temperature measured by TSA of at least 0.5 degrees Celsius, and further wherein the variants have at least at least 85%, at least 90%, at least 95% identity, at least 96%, at least 97%, at least 98%, or at least 99%, but less than 100%, sequence identity to the amino acid sequence of SEQ ID NO: 3. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

公开(公告)号：US11203790B2

公开(公告)日：2021-12-21

申请号：US16656708

申请日：2019-10-18

Applicant: NOVOZYMES A/S

Inventor： Shikha Gupta ,  Allan Svendsen ,  Vivek Srivastava ,  Marco Malten ,  Thomas Agersten Poulsen ,  Preethi Ramaiya ,  Beth Nelson ,  Vasudeva Prahlada Rao ,  Padmavathi Balumuri

IPC: C12P19/02 ,  C12P19/14 ,  C12P19/20 ,  C12N9/34

Abstract: The present invention relates to glucoamylase variants, polynucleotides encoding the variants, methods of producing the variants, and methods of using the variants. Also described are the use of glucoamylases of the invention for starch conversion to produce fermentation products, such as ethanol, and syrups, such as glucose. The invention also relates to a composition comprising a glucoamylase variant of the invention.