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公开(公告)号:US07163939B2
公开(公告)日:2007-01-16
申请号:US10980740
申请日:2004-11-03
申请人: Nan-Horng Lin , Gaoquan Li , Magdalena K. Przytulinska , Thomas J. Sowin , Gerard M. Sullivan , Zhi-Fu Tao , Yunsong Tong , Le Wang
发明人: Nan-Horng Lin , Gaoquan Li , Magdalena K. Przytulinska , Thomas J. Sowin , Gerard M. Sullivan , Zhi-Fu Tao , Yunsong Tong , Le Wang
IPC分类号: C07D513/08 , A61K31/529
CPC分类号: C07D487/08
摘要: Compounds having the formula are useful for inhibiting protein kinases. Also disclosed are methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
摘要翻译: 具有下式的化合物可用于抑制蛋白激酶。 还公开了制备化合物,含有化合物的组合物和使用该化合物的处理方法的方法。
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公开(公告)号:US20110293744A1
公开(公告)日:2011-12-01
申请号:US12689297
申请日:2010-01-19
IPC分类号: A61K31/423 , C07D413/10 , A61K31/4439 , A61K31/454 , A61P35/00 , A61K31/475 , A61K33/24 , A61K31/513 , A61K31/7068 , A61K31/519 , A61K38/14 , C07D263/57 , A61K31/675
CPC分类号: C07D413/04 , C07D263/57 , C07D263/58 , C07D413/10
摘要: Inhibitors of poly(ADP-ribose)polymerase having a structure of Formula (I), ways to make them and methods of treating patients using them are disclosed.
摘要翻译: 公开了具有式(I)结构的聚(ADP-核糖)聚合酶的抑制剂,其制备方法和使用它们治疗患者的方法。
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公开(公告)号:US08093396B2
公开(公告)日:2012-01-10
申请号:US12689290
申请日:2010-01-19
IPC分类号: C07D277/62 , A61K31/425
CPC分类号: C07D417/04 , C07D417/10
摘要: Inhibitors of poly(ADP-ribose)polymerase having a structure of Formula (I), ways to make them and methods of treating patients using them are disclosed.
摘要翻译: 公开了具有式(I)结构的聚(ADP-核糖)聚合酶的抑制剂,其制备方法和使用它们治疗患者的方法。
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公开(公告)号:US20100183743A1
公开(公告)日:2010-07-22
申请号:US12689290
申请日:2010-01-19
IPC分类号: A61K33/24 , A61K31/661 , A61K31/655 , A61K31/4436 , A61K31/428 , C07D417/02 , C07D277/62 , A61P35/00
CPC分类号: C07D417/04 , C07D417/10
摘要: Inhibitors of poly(ADP-ribose)polymerase having a structure of Formula (I), ways to make them and methods of treating patients using them are disclosed.
摘要翻译: 公开了具有式(I)结构的聚(ADP-核糖)聚合酶的抑制剂,其制备方法和使用它们治疗患者的方法。
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