公开(公告)号：US20240132972A1

公开(公告)日：2024-04-25

申请号：US18497332

申请日：2023-10-29

Applicant: Nanomed Diagnostics B.V.

Inventor： Willem Frederik Rurup ,  Loes Irene Segerink ,  Roderik Adriaan Kraaijenhagen ,  Herbert Michael Pinedo ,  Albert Van Den Berg ,  Renske Daniela Maria Steenbergen ,  Jacobus Adrianus Nieuwenhuijzen ,  Idris Bahce ,  Geert Kazemier

IPC: C12Q1/6886 ,  C12Q1/6806 ,  C12Q1/686

CPC classification number: C12Q1/6886 ,  C12Q1/6806 ,  C12Q1/686 ,  C12Q2600/112 ,  C12Q2600/118 ,  C12Q2600/154 ,  C12Q2600/156 ,  C12Q2600/16

Abstract: The invention provides in vitro methods of determining whether an individual has a pre-cancer or cancer comprising determining the presence or absence of one or more methylation markers of a methylation marker set in a urine sample of said individual; and determining whether the individual has pre-cancer or cancer based on the detection of the presence or absence of said one or more methylation markers in the urine sample, wherein the presence of said one or more methylation markers indicates that the individual has pre-cancer or cancer. The invention further provides methods for typing pre-cancer or cancer based on the presence or absence of one or more methylation markers of a methylation marker set in a urine sample.

公开(公告)号：US20190241963A1

公开(公告)日：2019-08-08

申请号：US16089222

申请日：2017-03-31

Applicant: NANOMED DIAGNOSTICS B.V.

Inventor： Willem Frederik Rurup ,  Loes Irene Segerink ,  Roderik Adriaan Kraaijenhagen ,  Herbert Michael Pinedo ,  Albert Van Den Berg ,  Renske Daniëla Maria Steenbergen ,  Jacobus Adrianus Nieuwenhuijzen ,  Idris Bahce ,  Geert Kazemier

IPC: C12Q1/6886 ,  C12Q1/6806 ,  C12Q1/686

CPC classification number: C12Q1/6886 ,  C12Q1/6806 ,  C12Q1/686 ,  C12Q2600/112 ,  C12Q2600/118 ,  C12Q2600/154 ,  C12Q2600/156 ,  C12Q2600/16

Abstract: The invention provides in vitro methods of determining whether an individual has a pre-cancer or cancer comprising determining the presence or absence of one or more methylation markers of a methylation marker set in a urine sample of said individual; and determining whether the individual has pre-cancer or cancer based on the detection of the presence or absence of said one or more methylation markers in the urine sample, wherein the presence of said one or more methylation markers indicates that the individual has pre-cancer or cancer. The invention further provides methods for typing pre-cancer or cancer based on the the presence or absence of one or more methylation markers of a methylation marker set in a urine sample.

公开(公告)号：US20240229153A9

公开(公告)日：2024-07-11

申请号：US18497332

申请日：2023-10-30

Applicant: Nanomed Diagnostics B.V.

Inventor： Willem Frederik Rurup ,  Loes Irene Segerink ,  Roderik Adriaan Kraaijenhagen ,  Herbert Michael Pinedo ,  Albert Van Den Berg ,  Renske Daniela Maria Steenbergen ,  Jacobus Adrianus Nieuwenhuijzen ,  Idris Bahce ,  Geert Kazemier

IPC: C12Q1/6886 ,  C12Q1/6806 ,  C12Q1/686

CPC classification number: C12Q1/6886 ,  C12Q1/6806 ,  C12Q1/686 ,  C12Q2600/112 ,  C12Q2600/118 ,  C12Q2600/154 ,  C12Q2600/156 ,  C12Q2600/16

Abstract: The invention provides in vitro methods of determining whether an individual has a pre-cancer or cancer comprising determining the presence or absence of one or more methylation markers of a methylation marker set in a urine sample of said individual; and determining whether the individual has pre-cancer or cancer based on the detection of the presence or absence of said one or more methylation markers in the urine sample, wherein the presence of said one or more methylation markers indicates that the individual has pre-cancer or cancer. The invention further provides methods for typing pre-cancer or cancer based on the presence or absence of one or more methylation markers of a methylation marker set in a urine sample.

公开(公告)号：US11821040B2

公开(公告)日：2023-11-21

申请号：US16089222

申请日：2017-03-31

Applicant: NANOMED DIAGNOSTICS B.V.

Inventor： Willem Frederik Rurup ,  Loes Irene Segerink ,  Roderik Adriaan Kraaijenhagen ,  Herbert Michael Pinedo ,  Albert Van Den Berg ,  Renske Daniëla Maria Steenbergen ,  Jacobus Adrianus Nieuwenhuijzen ,  Idris Bahce ,  Geert Kazemier

IPC: C12Q1/6886 ,  C12Q1/6806 ,  C12Q1/686

CPC classification number: C12Q1/6886 ,  C12Q1/6806 ,  C12Q1/686 ,  C12Q2600/112 ,  C12Q2600/118 ,  C12Q2600/154 ,  C12Q2600/156 ,  C12Q2600/16

Abstract: The invention provides in vitro methods of determining whether an individual has a pre-cancer or cancer comprising determining the presence or absence of one or more methylation markers of a methylation marker set in a urine sample of said individual; and determining whether the individual has pre-cancer or cancer based on the detection of the presence or absence of said one or more methylation markers in the urine sample, wherein the presence of said one or more methylation markers indicates that the individual has pre-cancer or cancer. The invention further provides methods for typing pre-cancer or cancer based on the the presence or absence of one or more methylation markers of a methylation marker set in a urine sample.