公开(公告)号：US10533219B2

公开(公告)日：2020-01-14

申请号：US15716058

申请日：2017-09-26

申请人： Natera, Inc.

发明人： Bernhard Zimmermann ,  Ryan Swenerton ,  Matthew Rabinowitz ,  Styrmir Sigurjonsson ,  George Gemelos ,  Apratim Ganguly ,  Himanshu Sethi

IPC分类号： C12Q1/68 ,  C12Q1/6869 ,  C12Q1/6806

摘要： The present disclosure provides methods and compositions for sequencing nucleic acid molecules and identifying individual sample nucleic acid molecules using Molecular Index Tags (MITs). Furthermore, reaction mixtures, kits, and adapter libraries are provided.

公开(公告)号：US11168362B2

公开(公告)日：2021-11-09

申请号：US16418104

申请日：2019-05-21

申请人： Natera, Inc.

发明人： Bernhard Zimmermann ,  Ryan Swenerton ,  Matthew Rabinowitz ,  Styrmir Sigurjonsson ,  George Gemelos ,  Apratim Ganguly ,  Himanshu Sethi

IPC分类号： C12Q1/6869 ,  C12Q1/6806

摘要： The present disclosure provides methods and compositions for sequencing nucleic acid molecules and identifying individual sample nucleic acid molecules using Molecular Index Tags (MITs). Furthermore, reaction mixtures, kits, and adapter libraries are provided.

公开(公告)号：US10577650B2

公开(公告)日：2020-03-03

申请号：US15716331

申请日：2017-09-26

申请人： Natera, Inc.

发明人： Bernhard Zimmermann ,  Ryan Swenerton ,  Matthew Rabinowitz ,  Styrmir Sigurjonsson ,  George Gemelos ,  Apratim Ganguly ,  Himanshu Sethi

IPC分类号： C12Q1/6869 ,  C12Q1/6806

摘要： The present disclosure provides methods and compositions for sequencing nucleic acid molecules and identifying individual sample nucleic acid molecules using Molecular Index Tags (MITs). Furthermore, reaction mixtures, kits, and adapter libraries are provided.

公开(公告)号：US10011870B2

公开(公告)日：2018-07-03

申请号：US15372279

申请日：2016-12-07

申请人： Natera, Inc.

发明人： Bernhard Zimmermann ,  Ryan Swenerton ,  Matthew Rabinowitz ,  Styrmir Sigurjonsson ,  George Gemelos ,  Apratim Ganguly ,  Himanshu Sethi

IPC分类号： C12Q1/68 ,  C12Q1/6869 ,  C12Q1/6806

摘要： The present disclosure provides methods and compositions for sequencing nucleic acid molecules and identifying individual sample nucleic acid molecules using Molecular Index Tags (MITs). Furthermore, reaction mixtures, kits, and adapter libraries are provided.

公开(公告)号：US11530442B2

公开(公告)日：2022-12-20

申请号：US16418104

申请日：2019-05-21

申请人： Natera, Inc.

发明人： Bernhard Zimmermann ,  Ryan Swenerton ,  Matthew Rabinowitz ,  Styrmir Sigurjonsson ,  George Gemelos ,  Apratim Ganguly ,  Himanshu Sethi

IPC分类号： C12Q1/6869 ,  C12Q1/6806

摘要： The present disclosure provides methods and compositions for sequencing nucleic acid molecules and identifying individual sample nucleic acid molecules using Molecular Index Tags (MITs). Furthermore, reaction mixtures, kits, and adapter libraries are provided.

公开(公告)号：US11519028B2

公开(公告)日：2022-12-06

申请号：US17494726

申请日：2021-10-05

申请人： Natera, Inc.

发明人： Bernhard Zimmermann ,  Ryan Swenerton ,  Matthew Rabinowitz ,  Styrmir Sigurjonsson ,  George Gemelos ,  Apratim Ganguly ,  Himanshu Sethi

IPC分类号： C12Q1/6806 ,  C12Q1/6869

摘要： The present disclosure provides methods and compositions for sequencing nucleic acid molecules and identifying individual sample nucleic acid molecules using Molecular Index Tags (MITs). Furthermore, reaction mixtures, kits, and adapter libraries are provided.

公开(公告)号：US11066703B2

公开(公告)日：2021-07-20

申请号：US16418104

申请日：2019-05-21

申请人： Natera, Inc.

发明人： Bernhard Zimmermann ,  Ryan Swenerton ,  Matthew Rabinowitz ,  Styrmir Sigurjonsson ,  George Gemelos ,  Apratim Ganguly ,  Himanshu Sethi

IPC分类号： C12Q1/6869 ,  C12Q1/6806

摘要： The present disclosure provides methods and compositions for sequencing nucleic acid molecules and identifying individual sample nucleic acid molecules using Molecular Index Tags (MITs). Furthermore, reaction mixtures, kits, and adapter libraries are provided.