公开(公告)号：US20230391768A2

公开(公告)日：2023-12-07

申请号：US17291927

申请日：2019-11-07

申请人： Nathanael S. Gray ,  Tinghu Zhang ,  Yao Liu ,  Zhixiang He ,  Mingfeng Hao ,  David Weinstock ,  Loretta Sze-Mun Li

发明人： Nathanael S. Gray ,  Tinghu Zhang ,  Yao Liu ,  Zhixiang He ,  Mingfeng Hao ,  David Weinstock ,  Loretta Sze-Mun Li

IPC分类号： C07D471/04 ,  C07D487/04 ,  A61K45/06

CPC分类号： C07D471/04 ,  C07D487/04 ,  A61K45/06

摘要： The present disclosure provides compounds of Formula (I′) (e.g., compounds of Formula (I)), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled derivatives, and prodrugs thereof. The provided compounds may be kinase (e.g., Janus kinase (JAK), e.g., Janus kinase 2 (JAK2)) inhibitors. Also provided are pharmaceutical compositions and kits including the provided compounds. Further provided are methods of using the provided compounds, pharmaceutical compositions, and kits (e.g., for treating a disease (e.g., proliferative disease) in a subject in need thereof).

公开(公告)号：US20130272576A1

公开(公告)日：2013-10-17

申请号：US13977155

申请日：2011-09-30

申请人： Wei Hu ,  Zhixiang He

发明人： Wei Hu ,  Zhixiang He

IPC分类号： G06K9/00

CPC分类号： G06K9/00268 ,  G06K9/00201 ,  G06K9/00241 ,  G06K9/00362 ,  G06K9/6202 ,  G06K9/6203 ,  G06T7/11 ,  G06T7/194 ,  G06T7/74 ,  G06T2207/10028 ,  G06T2207/20076 ,  G06T2207/30196

摘要： Systems, devices and methods are described including receiving a depth image and applying a template to pixels of the depth image to determine a location of a human head in the depth image. The template includes a circular shaped region and a first annular shaped region surrounding the circular shaped region. The circular shaped region specifies a first range of depth values. The first annular shaped region specifies a second range of depth values that are larger than depth values of the first range of depth values.

公开(公告)号：US09111131B2

公开(公告)日：2015-08-18

申请号：US13977155

申请日：2011-09-30

申请人： Wei Hu ,  Zhixiang He

发明人： Wei Hu ,  Zhixiang He

IPC分类号： G06K9/00 ,  G06T7/00 ,  G06K9/62

CPC分类号： G06K9/00268 ,  G06K9/00201 ,  G06K9/00241 ,  G06K9/00362 ,  G06K9/6202 ,  G06K9/6203 ,  G06T7/11 ,  G06T7/194 ,  G06T7/74 ,  G06T2207/10028 ,  G06T2207/20076 ,  G06T2207/30196

摘要： Systems, devices and methods are described including receiving a depth image and applying a template to pixels of the depth image to determine a location of a human head in the depth image. The template includes a circular shaped region and a first annular shaped region surrounding the circular shaped region. The circular shaped region specifies a first range of depth values. The first annular shaped region specifies a second range of depth values that are larger than depth values of the first range of depth values.

摘要翻译： 描述了系统，设备和方法，包括接收深度图像并将模板应用于深度图像的像素，以确定人类头部在深度图像中的位置。 模板包括圆形区域和围绕圆形区域的第一环形区域。 圆形区域指定深度值的第一范围。 第一环形区域指定深度值的第二范围，其大于深度值的第一范围的深度值。