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    Method for Synthesizing of Thioesters by Using Compound as Catalyst
    1.
    发明申请
    Method for Synthesizing of Thioesters by Using Compound as Catalyst 有权
    通过使用化合物作为催化剂合成硫酯的方法

    公开(公告)号：US20160340303A1

    公开(公告)日：2016-11-24

    申请号：US14885863

    申请日：2015-10-16

    申请人： National Central University

    发明人： Duen-Ren Hou ,  Sharada Prasanna Swain

    IPC分类号： C07C327/32 ,  C07C327/26 ,  B01J31/02 ,  C07C335/32

    CPC分类号： C07C327/32 ,  B01J31/0222 ,  B01J31/0237 ,  B01J31/0241 ,  B01J31/0271 ,  B01J2231/32 ,  B01J2231/4294 ,  C07C327/26 ,  C07C335/32

    摘要： A method for synthesizing of thioesters by using a compound as a catalyst is disclosed. The compound is represented by formula I below: In formula I, R5 represents H, a substituted or unsubstituted alkyl, a substituted or unsubstituted aryl, or a substituted or unsubstituted heteroaryl; X and Y each independently represents one of H, C1-10 alkyl, C5-10 aryl, C1-10 alkyl alcohol, thiohydroxy, carbonyl, sulfonyl, sulfamoyl, carbamoyl, C1-10 alkoxycarbonyl, C1-10 alkoxycarbamoyl, C1-10 alkylamino, C1-10 alkylsulfonyl, C1-10 haloalkylsulfonyl, ureido, amido, and C1-10 alkoxylcarbamoyl; and n is 0, 1, 2, 3, 4 or 5.

    摘要翻译： 在式I中，R 5表示H，取代或未取代的烷基，取代或未取代的芳基或取代或未取代的杂芳基; X和Y各自独立地表示H，C 1-10烷基，C 5-10芳基，C 1-10烷基醇，硫代羟基，羰基，磺酰基，氨磺酰基，氨基甲酰基，C 1-10烷氧基羰基，C 1-10烷氧基氨基甲酰基，C 1-10烷基氨基 ，C 1-10烷基磺酰基，C 1-10卤代烷基磺酰基，脲基，酰氨基和C 1-10烷氧基氨基甲酰基; 且n为0,1,2,3,4或5。

    Method for synthesizing of thioesters by using compound as catalyst
    3.
    发明授权
    Method for synthesizing of thioesters by using compound as catalyst 有权
    通过使用化合物作为催化剂合成硫酯的方法

    公开(公告)号：US09567297B2

    公开(公告)日：2017-02-14

    申请号：US14885863

    申请日：2015-10-16

    申请人： National Central University

    发明人： Duen-Ren Hou ,  Sharada Prasanna Swain

    IPC分类号： C07C327/32 ,  C07C335/32 ,  C07C327/26 ,  B01J31/02

    CPC分类号： C07C327/32 ,  B01J31/0222 ,  B01J31/0237 ,  B01J31/0241 ,  B01J31/0271 ,  B01J2231/32 ,  B01J2231/4294 ,  C07C327/26 ,  C07C335/32

    摘要： A method for synthesizing of thioesters by using a compound as a catalyst is disclosed. The compound is represented by formula I below: In formula I, R5 represents H, a substituted or unsubstituted alkyl, a substituted or unsubstituted aryl, or a substituted or unsubstituted heteroaryl; X and Y each independently represents one of H, C1-10 alkyl, C5-10 aryl, C1-10 alkyl alcohol, thiohydroxy, carbonyl, sulfonyl, sulfamoyl, carbamoyl, C1-10 alkoxycarbonyl, C1-10 alkoxycarbamoyl, C1-10 alkylamino, C1-10 alkylsulfonyl, C1-10 haloalkylsulfonyl, ureido, amido, and C1-10 alkoxylcarbamoyl; and n is 0, 1, 2, 3, 4 or 5.

    摘要翻译： 在式I中，R 5表示H，取代或未取代的烷基，取代或未取代的芳基或取代或未取代的杂芳基; X和Y各自独立地表示H，C 1-10烷基，C 5-10芳基，C 1-10烷基醇，硫代羟基，羰基，磺酰基，氨磺酰基，氨基甲酰基，C 1-10烷氧基羰基，C 1-10烷氧基氨基甲酰基，C 1-10烷基氨基 ，C 1-10烷基磺酰基，C 1-10卤代烷基磺酰基，脲基，酰氨基和C 1-10烷氧基氨基甲酰基; 且n为0,1,2,3,4或5。

    Substituted 1,2,3-Triazoles as Antitumor Agents
    4.
    发明申请
    Substituted 1,2,3-Triazoles as Antitumor Agents 有权
    取代的1,2,3-三唑作为抗肿瘤剂

    公开(公告)号：US20160340321A1

    公开(公告)日：2016-11-24

    申请号：US14715019

    申请日：2015-05-18

    申请人： National Central University

    发明人： Duen-Ren Hou ,  Sharada Prasanna Swain

    IPC分类号： C07D249/04

    CPC分类号： C07D249/04

    摘要： Compounds represented by Formula I: and/or a pharmaceutically acceptable salts, a prodrug, a solvate and a combination thereof, a pharmaceutical composition including the triazole derivative, and a method of treating a cancer disease in an individual are disclosed.

    摘要翻译： 和/或其药学上可接受的盐，前药，溶剂合物及其组合，公开了包含该三唑衍生物的药物组合物和治疗个体中的癌症疾病的方法。