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公开(公告)号:US11819570B2
公开(公告)日:2023-11-21
申请号:US17055032
申请日:2019-05-31
申请人: National University Corporation Tokai National Higher Education and Research System , National University Corporation Tokyo Medical and Dental University
发明人: Takayoshi Suganami , Miyako Tanaka , Akira Matsumoto , Hiroko Matsumoto , Yuki Morooka , Yuji Miyahara
CPC分类号: A61K9/06 , A61K38/28 , A61K47/32 , A61M37/0015 , A61M2037/0023
摘要: A sugar-responsive gel that is highly resistant to temperature changes, and a sugar-responsive drug delivery device including such a gel. The sugar-responsive gel, which comprises a gel composition including a monomer having a hydroxyl group in addition to a phenylboronic-acid-based monomer, can exhibit suitable temperature resistance. A sugar-responsive drug delivery device including such a sugar-responsive gel is less susceptible to the effects of temperature changes, and therefore can prevent undesirable excessive delivery of a drug such as insulin.