公开(公告)号：US20210238165A1

公开(公告)日：2021-08-05

申请号：US16604208

申请日：2018-04-09

申请人： Navitor Pharmaceuticals, Inc.

发明人： Sarah MAHONEY ,  Lisa MOLZ ,  Sridhar NARAYAN ,  Eddine SAIAH

IPC分类号： C07D403/10 ,  C07D498/04 ,  C07D209/42 ,  C07D405/12 ,  C07D471/04 ,  C07D403/06 ,  C07D401/12 ,  C07D413/12 ,  C07D235/12 ,  C07D413/14 ,  C07D401/04

摘要： The present invention provides compounds, compositions thereof, and methods of using the same. Compositions comprising a compound of this invention or a pharmaceutically acceptable derivative thereof and a pharmaceutically acceptable carrier, adjuvant, or vehicle. The amount of the compound in compositions of this invention is such that it is effective to measurably inhibit Rheb, in a biological sample or in a patient.

公开(公告)号：US20210047347A1

公开(公告)日：2021-02-18

申请号：US16941821

申请日：2020-07-29

申请人： Navitor Pharmaceuticals, Inc.

发明人： Kristina Michelle FETALVERO ,  Sridhar NARAYAN ,  David John O'NEILL ,  Eddine SAIAH ,  Shomit SENGUPTA

IPC分类号： C07F7/08 ,  A61K38/00 ,  A61K31/198 ,  A61K31/223 ,  C07C261/04 ,  C07C311/13 ,  C07C311/19 ,  C07C311/51 ,  C07C229/28 ,  C07C233/40 ,  C07C233/83 ,  C07C237/06 ,  C07C237/12 ,  C07C237/30 ,  A61K31/197 ,  A61K31/221 ,  A61K31/275 ,  A61K31/341 ,  A61K31/41 ,  A61K31/695 ,  A61K45/06 ,  C07C229/12 ,  C07C229/14 ,  C07C229/18 ,  C07C229/20 ,  C07C233/07 ,  C07C233/47 ,  C07C233/49 ,  C07C233/51 ,  C07C233/63 ,  C07C255/61 ,  C07C311/06 ,  C07C311/10 ,  C07C311/14 ,  C07D257/04 ,  C07D307/33

摘要： The present invention provides compounds, compositions thereof, and methods of using the same.