公开(公告)号：US20240197349A1

公开(公告)日：2024-06-20

申请号：US18588153

申请日：2024-02-27

申请人： Neuravi Limited

发明人： Ronald KELLY ,  Karl KEATING

IPC分类号： A61B17/221 ,  A61B17/00

CPC分类号： A61B17/221 ,  A61B2017/00867 ,  A61B2017/2212

摘要： Devices described herein include an actuated clot retrieval catheter system. The system includes a catheter having a frame disposed proximate the distal end of the catheter. The frame expands to form a seal with the inner wall of a vessel. In some examples, the frame also captures a clot for removal from the vessel. The frame is manufactured from a shape memory material that can be heat set into a predetermined shape. An electrical connection to an electronic circuit causes a current to run through the frame. The electrical resistance of the shape memory material causes the frame to heat and transition from a martensite to an austenite phase. When the frame is heat set into an expanded configuration, the current causes the frame heat and expand. When the frame is heat set into a closed configuration, the current causes the frame heat and collapse upon a clot.

公开(公告)号：US20230414235A1

公开(公告)日：2023-12-28

申请号：US18239808

申请日：2023-08-30

申请人： Neuravi Limited

发明人： Brendan CASEY ,  Karl KEATING ,  Ronald KELLY ,  David VALE

IPC分类号： A61B17/221 ,  A61M25/01

CPC分类号： A61B17/221 ,  A61B2017/22045 ,  A61M25/0147

摘要： A clot retrieval catheter can have an expansile distal tip for flow restriction/arrest and improved aspiration efficiency and a large, distal facing mouth into which clots or other obstructions can be retrieved. The tip can be formed from a distal ring of leaflets or hoops. One or more pull cables can be retracted to actuate and radially expand the expansile distal tip. The clot retrieval catheter can have a catheter shaft with flexibility-adding features proximal of the tip. The catheter shaft can be a multi-lumen configuration with a large catheter lumen for passing auxiliary devices and directing aspiration and one or more guide lumens which can route the pull cables to the leaflets or hoops of the expansile tip. A flexible, low-modulus membrane can be disposed around at least a portion of the expansile tip and catheter shaft.

公开(公告)号：US20230404607A1

公开(公告)日：2023-12-21

申请号：US18240765

申请日：2023-08-31

申请人： Neuravi Limited

发明人： Ronald KELLY ,  Karl KEATING

IPC分类号： A61B17/221 ,  A61M29/00

CPC分类号： A61B17/221 ,  A61M29/00 ,  A61B2017/00323

摘要： According to the present disclosure, there is provided a device which can have a funnel catheter having an expandable distal tip. The funnel catheter can originally be placed in a collapsed configuration for delivery through vasculature to a target thrombus location. Once positioned, the expandable tip can be radially expanded to create a funnel for aspirating or retrieving clots from a vessel. The funnel catheter can be at least partially enclosed by an outer sheath for purposes of delivery to the target site or to assist in expansion of the funnel catheter tip.

公开(公告)号：US20210402158A1

公开(公告)日：2021-12-30

申请号：US16914881

申请日：2020-06-29

申请人： Neuravi Limited

发明人： Karl KEATING ,  Ronald KELLY

IPC分类号： A61M25/10

摘要： Catheter based systems for isolated stenting of an intravascular lesion can include two expandable occlusion devices with a balloon expandable stent or self-expanding stent therebetween. Expandable occlusion devices can be expanded in a distal direction and a proximal direction in relation to the lesion to occlude vasculature. A treatment agent can be injected into a cavity formed between the expandable occlusion device. A coating can be applied to one or both occlusion devices to prevent adherence to the treatment agent. The stent can be deployed across the lesion while the occlusion devices are in place. Fragments dislodged during stenting can be aspirated.

公开(公告)号：US20210401444A1

公开(公告)日：2021-12-30

申请号：US16914663

申请日：2020-06-29

申请人： Neuravi Limited

发明人： Karl KEATING ,  Ronald KELLY

IPC分类号： A61B17/22

摘要： Catheter based systems for isolated stenting of an intravascular lesion can include two expandable occlusion devices with a balloon expandable stent therebetween. Expandable occlusion devices can be expanded in a distal direction and a proximal direction in relation to the lesion to occlude vasculature. One or both of the occlusion devices can include a fluid impermeable membrane to occlude blood flow. The stent can be deployed across the lesion while the occlusion devices are in place. Fragments dislodged during stenting can be aspirated.

公开(公告)号：US20210153884A1

公开(公告)日：2021-05-27

申请号：US17104097

申请日：2020-11-25

申请人： NEURAVI LIMITED

发明人： Brendan CASEY ,  Karl KEATING ,  Ronald KELLY ,  David VALE

IPC分类号： A61B17/221 ,  A61M25/01

摘要： A clot retrieval catheter can have an expansile distal tip for flow restriction/arrest and improved aspiration efficiency and a large, distal facing mouth into which clots or other obstructions can be retrieved. The tip can be formed from a distal ring of leaflets or hoops. One or more pull cables can be retracted to actuate and radially expand the expansile distal tip. The clot retrieval catheter can have a catheter shaft with flexibility-adding features proximal of the tip. The catheter shaft can be a multi-lumen configuration with a large catheter lumen for passing auxiliary devices and directing aspiration and one or more guide lumens which can route the pull cables to the leaflets or hoops of the expansile tip. A flexible, low-modulus membrane can be disposed around at least a portion of the expansile tip and catheter shaft.

公开(公告)号：US20240189544A1

公开(公告)日：2024-06-13

申请号：US18581692

申请日：2024-02-20

申请人： Neuravi Limited

发明人： Brendan CASEY ,  Ronald KELLY ,  David VALE ,  Denis FOLEY ,  Michael GILVARRY

IPC分类号： A61M25/00 ,  A61B17/12 ,  A61M25/10 ,  A61M39/22

CPC分类号： A61M25/005 ,  A61B17/12109 ,  A61B17/12136 ,  A61M25/0032 ,  A61M25/0097 ,  A61M25/1002 ,  A61M25/10185 ,  A61M39/223 ,  A61M2025/0039 ,  A61M2025/0059 ,  A61M2025/1061

摘要： A balloon guide catheter having a sleeved inflation lumen secured with a wire wrap for improved inflation lumen kink protection and a welded balloon construction provides a robust and flexible catheter with an exceptionally large inner lumen relative to its outer profile and enables rapid and reliable balloon inflation and deflation in a highly deliverable and kink resistant catheter. Balloon guide catheters having multiple sleeved inflation lumens and proximal luers for utilizing the multiple inflation lumens are also provided.

公开(公告)号：US20230140794A1

公开(公告)日：2023-05-04

申请号：US17518401

申请日：2021-11-03

申请人： Neuravi Limited

发明人： Karl KEATING ,  Ronald KELLY ,  David VALE ,  Brendan CASEY

IPC分类号： A61B17/12

摘要： The designs and methods disclosed herein are for a clot retrieval catheter with a large bore shaft and a distal braid-supported tip that is expandable. A distal expansile section of the braid-supported tip can have a delivery inner diameter approximately equal to the inner diameter of the shaft. The braid of the tip can have a decreasing braid angle distally so that the tip can expand to a larger expanded inner diameter when impinged radially by an ingested clot to manage the clot and prevent shearing of clot fragments. The wires of the tip braids can follow one spiral direction distally and then invert proximally back on themselves to form the other spiral direction of the braid. This inversion of the wires results in atraumatic distal hoops at the distal termination of the braid. Designs can further have spines capable of resisting elongation of the catheter shaft during a procedure.

公开(公告)号：US20220354516A1

公开(公告)日：2022-11-10

申请号：US17810587

申请日：2022-07-01

申请人： Neuravi Limited

发明人： David VALE ,  Aidan DUFFY ,  Ronald KELLY ,  Shane CONWAY ,  Brendan CASEY ,  Thomas O'MALLEY

IPC分类号： A61B17/221

摘要： An expandable mechanical device for use during a thrombectomy medical procedure having enhanced visibility during imaging. Furthermore, the configuration of the eyelet and/or strut optimizes retention of the marker in the eyelet during the medical procedure without increasing overall profile of strut.

公开(公告)号：US20210153883A1

公开(公告)日：2021-05-27

申请号：US17101960

申请日：2020-11-23

申请人： NEURAVI LIMITED

发明人： Brendan CASEY ,  Karl KEATING ,  Ronald KELLY ,  David VALE

IPC分类号： A61B17/221

摘要： A catheter including a distal tip section disposed on or adjacent the distal end of the catheter, the distal tip section being invertible about a transition between a catheter body and the distal tip section between a first configuration and a second configuration. Retracting the distal tip section causes the distal tip section to invert about the transition from the first to the second configuration, the second configuration comprising an expansile tip with an open funnel-like distal mouth comprising a larger diameter than a diameter of the transition.