-
公开(公告)号：US10961322B2
公开(公告)日：2021-03-30
申请号：US16434654
申请日：2019-06-07
发明人： Fabio Montrasio , Jan Grimm
摘要： Provided are novel human-derived dipeptide repeat (DPR) specific antibodies as well as synthetic variants and biotechnological derivatives thereof, preferably capable of binding C9ORF72 DPRs, as well as methods related thereto. Assays, kits, and solid supports related to antibodies specific for DPRs and DPR proteins such C9ORF72 DPRs are also disclosed. The antibody of the present invention can be used in pharmaceutical and diagnostic compositions for DPR protein-targeted immunotherapy and diagnostics.
-
公开(公告)号：US20190284302A1
公开(公告)日：2019-09-19
申请号：US16424169
申请日：2019-05-28
发明人： Fabio Montrasio , Maria Grazia Barenco Montrasio , Jan Grimm , Roger Nitsch , Christoph Hock , Tobias Welt , Jordan Mcafoose , Marcel Maier
IPC分类号： C07K16/40 , G01N33/68 , A61K45/06 , A61K51/10 , A61K39/00 , C07K14/435 , C12N9/02 , A61K39/395 , G01N33/573 , G01N33/577 , A61K47/68 , A61K49/08
摘要： Provided are novel human copper-zinc superoxide dismutase, also known as superoxide dismutase 1 or SOD1, specific antibodies as well as fragments, derivatives and variants thereof as well as methods related thereto. Assays, kits, and solid supports related to antibodies specific for SOD1 are also disclosed. The antibody, immunoglobulin chain(s), as well as binding fragments, derivatives and variants thereof can be used in pharmaceutical and diagnostic compositions for SOD1 targeted immunotherapy and diagnosis, respectively.
-
公开(公告)号：US10392447B2
公开(公告)日：2019-08-27
申请号：US15508343
申请日：2015-09-30
发明人： Fabio Montrasio , Jan Grimm
摘要： Provided are novel human-derived dipeptide repeat (DPR) specific antibodies as well as synthetic variants and biotechnological derivatives thereof, preferably capable of binding C9ORF72 DPRs, as well as methods related thereto. Assays, kits, and solid supports related to antibodies specific for DPRs and DPR proteins such C9ORF72 DPRs are also disclosed. The antibody of the present invention can be used in pharmaceutical and diagnostic compositions for DPR protein-targeted immunotherapy and diagnostics.
-
公开(公告)号：US10344097B2
公开(公告)日：2019-07-09
申请号：US15014215
申请日：2016-02-03
发明人： Fabio Montrasio , Maria Grazia Barenco Montrasio , Jan Grimm , Roger Nitsch , Christoph Hock , Tobias Welt , Jordan Mcafoose , Marcel Maier
IPC分类号： A61K39/395 , C07K16/40 , A61K39/00 , C07K14/435 , C12N9/02 , A61K45/06 , A61K49/08 , A61K51/10 , G01N33/573 , G01N33/577 , A61K47/68 , G01N33/68
摘要： Provided are novel human copper-zinc superoxide dismutase, also known as superoxide dismutase 1 or SOD1, specific antibodies as well as fragments, derivatives and variants thereof as well as methods related thereto. Assays, kits, and solid supports related to antibodies specific for SOD1 are also disclosed. The antibody, immunoglobulin chain(s), as well as binding fragments, derivatives and variants thereof can be used in pharmaceutical and diagnostic compositions for SOD1 targeted immunotherapy and diagnosis, respectively.
-
公开(公告)号：US20220267471A1
公开(公告)日：2022-08-25
申请号：US17738700
申请日：2022-05-06
发明人： Fabio Montrasio , Maria Grazia Barenco Montrasio , Jan Grimm , Roger Nitsch , Christoph Hock , Tobias Welt , Jordan Mcafoose , Marcel Maier
IPC分类号： C07K16/40 , A61K39/00 , C07K14/435 , C12N9/02 , A61K47/68 , G01N33/68 , A61K39/395 , A61K45/06 , A61K49/08 , A61K51/10 , G01N33/573 , G01N33/577
摘要： Provided are novel human copper-zinc superoxide dismutase, also known as superoxide dismutase 1 or SOD1, specific antibodies as well as fragments, derivatives and variants thereof as well as methods related thereto. Assays, kits, and solid supports related to antibodies specific for SOD1 are also disclosed. The antibody, immunoglobulin chain(s), as well as binding fragments, derivatives and variants thereof can be used in pharmaceutical and diagnostic compositions for SOD1 targeted immunotherapy and diagnosis, respectively.
-
公开(公告)号：US20240279361A1
公开(公告)日：2024-08-22
申请号：US18492146
申请日：2023-10-23
发明人： Fabio Montrasio , Jan Grimm
CPC分类号： C07K16/44 , A61P25/28 , G01N33/6896 , C07K2317/21 , C07K2317/33 , C07K2317/76 , C07K2317/92 , G01N2800/2814
摘要： Provided are novel human-derived dipeptide repeat (DPR) specific antibodies as well as synthetic variants and biotechnological derivatives thereof, preferably capable of binding C9ORF72 DPRs, as well as methods related thereto. Assays, kits, and solid supports related to antibodies specific for DPRs and DPR proteins such C9ORF72 DPRs are also disclosed. The antibody of the present invention can be used in pharmaceutical and diagnostic compositions for DPR protein-targeted immunotherapy and diagnostics.
-
公开(公告)号：US20240254256A1
公开(公告)日：2024-08-01
申请号：US18442889
申请日：2024-02-15
发明人： Fabio Montrasio , Maria Grazia Barenco Montrasio , Jan Grimm , Roger Nitsch , Christoph Hock , Tobias Welt , Jordan McAfoose , Marcel Maier
IPC分类号： C07K16/40 , A61K39/00 , A61K39/395 , A61K45/06 , A61K47/68 , A61K49/08 , A61K51/10 , C07K14/435 , C12N9/02 , G01N33/573 , G01N33/577 , G01N33/68
CPC分类号： C07K16/40 , A61K39/0005 , A61K39/3955 , A61K45/06 , A61K47/6871 , A61K49/085 , A61K51/10 , C07K14/435 , C12N9/0089 , G01N33/573 , G01N33/577 , G01N33/6893 , A61K2039/505 , C07K2317/21 , C07K2317/24 , C07K2317/30 , C07K2317/33 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/92 , G01N2333/90283 , G01N2800/28 , G01N2800/285
摘要： Provided are novel human copper-zinc superoxide dismutase, also known as superoxide dismutase 1 or SOD1, specific antibodies as well as fragments, derivatives and variants thereof as well as methods related thereto. Assays, kits, and solid supports related to antibodies specific for SOD1 are also disclosed. The antibody, immunoglobulin chain(s), as well as binding fragments, derivatives and variants thereof can be used in pharmaceutical and diagnostic compositions for SOD1 targeted immunotherapy and diagnosis, respectively.
-
公开(公告)号：US11352441B2
公开(公告)日：2022-06-07
申请号：US16424169
申请日：2019-05-28
发明人： Fabio Montrasio , Maria Grazia Barenco Montrasio , Jan Grimm , Roger Nitsch , Christoph Hock , Tobias Welt , Jordan Mcafoose , Marcel Maier
IPC分类号： C07K16/40 , A61K39/00 , C07K14/435 , C12N9/02 , A61K47/68 , G01N33/68 , A61K39/395 , A61K45/06 , A61K49/08 , A61K51/10 , G01N33/573 , G01N33/577
摘要： Provided are novel human copper-zinc superoxide dismutase, also known as superoxide dismutase 1 or SOD1, specific antibodies as well as fragments, derivatives and variants thereof as well as methods related thereto. Assays, kits, and solid supports related to antibodies specific for SOD1 are also disclosed. The antibody, immunoglobulin chain(s), as well as binding fragments, derivatives and variants thereof can be used in pharmaceutical and diagnostic compositions for SOD1 targeted immunotherapy and diagnosis, respectively.
-
公开(公告)号：US20160168267A1
公开(公告)日：2016-06-16
申请号：US15014215
申请日：2016-02-03
发明人： Fabio Montrasio , Maria Grazia Barenco Montrasio , Jan Grimm , Roger Nitsch , Christoph Hock , Tobias Welt , Jordan Mcafoose , Marcel Maier
IPC分类号： C07K16/40 , G01N33/573 , G01N33/577 , A61K39/395
CPC分类号： C07K16/40 , A61K39/0005 , A61K39/3955 , A61K45/06 , A61K47/6871 , A61K49/085 , A61K51/10 , A61K2039/505 , C07K14/435 , C07K2317/21 , C07K2317/24 , C07K2317/30 , C07K2317/33 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/92 , C12N9/0089 , G01N33/573 , G01N33/577 , G01N33/6893 , G01N2333/90283 , G01N2800/28 , G01N2800/285
摘要： Provided are novel human copper-zinc superoxide dismutase, also known as superoxide dismutase 1 or SOD1, specific antibodies as well as fragments, derivatives and variants thereof as well as methods related thereto. Assays, kits, and solid supports related to antibodies specific for SOD1 are also disclosed. The antibody, immunoglobulin chain(s), as well as binding fragments, derivatives and variants thereof can be used in pharmaceutical and diagnostic compositions for SOD1 targeted immunotherapy and diagnosis, respectively.
摘要翻译： 提供新型人铜 - 锌超氧化物歧化酶，也称为超氧化物歧化酶1或SOD1，特异性抗体以及其片段，衍生物和变体以及与之相关的方法。 还公开了与SOD1特异性抗体相关的测定，试剂盒和固体支持物。 抗体，免疫球蛋白链以及其结合片段，衍生物和变体可分别用于SOD1靶向免疫治疗和诊断的药物和诊断组合物中。
-
-
-
-
-
-
-
-
搜索结果
9 条记录 (耗时 0.022 秒)
