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公开(公告)号：US07307075B2
公开(公告)日：2007-12-11
申请号：US10329455
申请日：2002-12-23
IPC分类号： A61P25/00 , A61K31/535 , C07D265/36
CPC分类号： C07D451/02 , C07D401/04 , C07D413/06 , C07D417/06 , C07D513/04
摘要： The present invention relates to tetrahydroquinoline compounds as muscarinic receptor agonists; compositions comprising the same; methods of inhibiting an activity of a muscarinic receptor with said compounds; methods of treating a disease condition associated with a muscarinic receptor using said compounds; and methods for identifying a subject suitable for treatment using said compounds.
摘要翻译： 本发明涉及四氢喹啉化合物作为毒蕈碱受体激动剂; 包含它们的组合物; 用所述化合物抑制毒蕈碱受体的活性的方法; 使用所述化合物治疗与毒蕈碱受体相关的疾病状况的方法; 以及用于鉴定适于使用所述化合物治疗的受试者的方法。
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公开(公告)号：US07576100B2
公开(公告)日：2009-08-18
申请号：US11417867
申请日：2006-05-03
IPC分类号： A61P25/00 , A61K31/47 , C07D215/00
CPC分类号： C07D451/02 , C07D401/04 , C07D413/06 , C07D417/06 , C07D513/04
摘要： The present invention relates to tetrahydroquinoline compounds as muscarinic receptor agonists; compositions comprising the same; methods of inhibiting an activity of a muscarinic receptor with said compounds; methods of treating a disease condition associated with a muscarinic receptor using said compounds; and methods for identifying a subject suitable for treatment using said compounds.
摘要翻译： 本发明涉及四氢喹啉化合物作为毒蕈碱受体激动剂; 包含它们的组合物; 用所述化合物抑制毒蕈碱受体的活性的方法; 使用所述化合物治疗与毒蕈碱受体相关的疾病状况的方法; 以及用于鉴定适于使用所述化合物治疗的受试者的方法。
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公开(公告)号：US07576078B2
公开(公告)日：2009-08-18
申请号：US11417865
申请日：2006-05-03
IPC分类号： A61P25/00 , A61K31/54 , C07D279/16
CPC分类号： C07D451/02 , C07D401/04 , C07D413/06 , C07D417/06 , C07D513/04
摘要： The present invention relates to tetrahydroquinoline compounds as muscarinic receptor agonists; compositions comprising the same; methods of inhibiting an activity of a muscarinic receptor with said compounds; methods of treating a disease condition associated with a muscarinic receptor using said compounds; and methods for identifying a subject suitable for treatment using said compounds.
摘要翻译： 本发明涉及四氢喹啉化合物作为毒蕈碱受体激动剂; 包含它们的组合物; 用所述化合物抑制毒蕈碱受体的活性的方法; 使用所述化合物治疗与毒蕈碱受体相关的疾病状况的方法; 以及用于鉴定适于使用所述化合物治疗的受试者的方法。
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公开(公告)号：US07550459B2
公开(公告)日：2009-06-23
申请号：US11019556
申请日：2004-12-21
IPC分类号： A61P25/00 , A61K31/535 , C07D265/36
CPC分类号： C07D413/06 , C07D401/04 , C07D401/06 , C07D417/06 , C07D451/02 , C07D451/04 , C07D451/06
摘要： The present invention relates to tetrahydroquinoline compounds as muscarinic receptor agonists; compositions comprising the same; methods of inhibiting an activity of a muscarinic receptor with said compounds; methods of treating a disease condition associated with a muscarinic receptor using said compounds; and methods for identifying a subject suitable for treatment using said compounds.
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公开(公告)号：US08680115B2
公开(公告)日：2014-03-25
申请号：US12473220
申请日：2009-05-27
IPC分类号： A61P43/00 , A61K31/435 , C07D401/04 , C07D413/06 , C07D417/06 , C07D451/02 , C07D513/04
CPC分类号： C07D413/06 , C07D401/04 , C07D401/06 , C07D417/06 , C07D451/02 , C07D451/04 , C07D451/06
摘要： The present invention relates to tetrahydroquinoline compounds as muscarinic receptor agonists; compositions comprising the same; methods of inhibiting an activity of a muscarinic receptor with said compounds; methods of treating a disease condition associated with a muscarinic receptor using said compounds; and methods for identifying a subject suitable for treatment using said compounds.
摘要翻译： 本发明涉及四氢喹啉化合物作为毒蕈碱受体激动剂; 包含它们的组合物; 用所述化合物抑制毒蕈碱受体的活性的方法; 使用所述化合物治疗与毒蕈碱受体相关的疾病状况的方法; 以及用于鉴定适于使用所述化合物治疗的受试者的方法。
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公开(公告)号：US20090239903A1
公开(公告)日：2009-09-24
申请号：US12473220
申请日：2009-05-27
IPC分类号： A61K31/439 , C07D401/06 , A61K31/4709 , C07D453/02 , C07K14/705 , A61P25/28
CPC分类号： C07D413/06 , C07D401/04 , C07D401/06 , C07D417/06 , C07D451/02 , C07D451/04 , C07D451/06
摘要： The present invention relates to tetrahydroquinoline compounds as muscarinic receptor agonists; compositions comprising the same; methods of inhibiting an activity of a muscarinic receptor with said compounds; methods of treating a disease condition associated with a muscarinic receptor using said compounds; and methods for identifying a subject suitable for treatment using said compounds.
摘要翻译： 本发明涉及四氢喹啉化合物作为毒蕈碱受体激动剂; 包含它们的组合物; 用所述化合物抑制毒蕈碱受体的活性的方法; 使用所述化合物治疗与毒蕈碱受体相关的疾病状况的方法; 以及用于鉴定适于使用所述化合物治疗的受试者的方法。
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