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公开(公告)号:US06998138B2
公开(公告)日:2006-02-14
申请号:US10636976
申请日:2003-08-08
IPC分类号: A61F13/02
CPC分类号: A61K8/046 , A61K8/37 , A61K8/445 , A61K9/0014 , A61K9/12 , A61K9/122 , A61K47/14 , A61M35/003 , A61Q17/04 , Y10S514/88
摘要: The present invention provides a topical drug delivery system which comprises: a therapeutically effective amount of an anti-alopecia agent; at least one dermal penetration enhancer, which is a safe skin-tolerant ester sunscreen ester; and a volatile liquid. The invention also provides a method for administering at least one systemic acting anti-alopecia agent to an animal which comprises applying an effective amount of the anti-alopecia agent in the form of the drug delivery system of the present invention.
摘要翻译: 本发明提供一种局部给药系统,其包括:治疗有效量的抗脱发剂; 至少一种皮肤渗透促进剂,其是安全的耐受皮肤的酯类防晒酯; 和挥发性液体。 本发明还提供了向动物施用至少一种全身作用的抗脱发剂的方法,其包括以本发明的药物递送系统的形式施用有效量的抗脱发剂。
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公开(公告)号:US07094422B2
公开(公告)日:2006-08-22
申请号:US10644085
申请日:2003-08-20
IPC分类号: A61F13/02
CPC分类号: A61K8/046 , A61K8/37 , A61K8/445 , A61K9/0014 , A61K9/12 , A61K9/122 , A61K47/14 , A61M35/003 , A61Q17/04
摘要: The present invention provides a topical drug delivery system which comprises: a therapeutically effective amount of an antifungal agent; at least one dermal penetration enhancer, which is a safe skin-tolerant ester sunscreen ester; and a volatile liquid. The invention also provides a method for administering at least one systemic acting antifungal agent to an animal which comprises applying an effective amount of the antifungal agent in the form of the drug delivery system of the present invention.
摘要翻译: 本发明提供一种局部给药系统,其包括:治疗有效量的抗真菌剂; 至少一种皮肤渗透促进剂,其是安全的耐受皮肤的酯类防晒酯; 和挥发性液体。 本发明还提供了向动物施用至少一种全身作用的抗真菌剂的方法,其包括以本发明的药物递送系统的形式施用有效量的抗真菌剂。
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公开(公告)号:US20080226699A1
公开(公告)日:2008-09-18
申请号:US10580845
申请日:2004-11-26
申请人: Barrie Charles Finnin , Timothy Matthias Morgan , Nina Frances Wilkins , Nora Yat Knork Chew , Igor Gonda
发明人: Barrie Charles Finnin , Timothy Matthias Morgan , Nina Frances Wilkins , Nora Yat Knork Chew , Igor Gonda
IPC分类号: A61M37/00 , A61K31/445
CPC分类号: A61M37/0015 , A61K9/0014 , A61K9/0021 , A61K47/10 , A61M2037/0023 , A61M2037/0053
摘要: Invention relates to a method for transdermal delivery of a topically applied physiologically active agent comprising: providing a micro-projection apparatus comprising an array of microprojections (3) extending from a substrate; applying the array of micro-projections to an area of skin to form an array of microscopic holes therein; and contacting the area of skin with a transdermal composition comprising a physiologically active agent and at least one penetration enhancer wherein the formation of the microscopic holes and penetration enhancer facilitate transdermal delivery of the physiologically active agent.
摘要翻译: 本发明涉及一种局部施用的生理活性剂透皮递送方法,包括:提供包括从基底延伸的微突出物阵列(3)的微投影装置; 将微阵列阵列施加到皮肤区域以在其中形成微孔的阵列; 以及使皮肤区域与包含生理活性剂和至少一种渗透促进剂的透皮组合物接触,其中形成微孔和渗透促进剂促进生理活性剂的透皮递送。
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