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公开(公告)号：USD450867S1
公开(公告)日：2001-11-20
申请号：US29138260
申请日：2001-03-09
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公开(公告)号：USD451220S1
公开(公告)日：2001-11-27
申请号：US29138276
申请日：2001-03-09
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公开(公告)号：US06354343B1
公开(公告)日：2002-03-12
申请号：US09481088
申请日：2000-01-11
申请人： Rudolph A. Strnad , Spencer P. Magleby , John F. Marshall , W. Douglas Stout , Carl D. Sorensen , Ryan W. Warnick , Lee Baroldy , Lisa Cloward , David S. Bent , Adam Gaglione , Robert Cvetko , Aaron T. Schellenberg
发明人： Rudolph A. Strnad , Spencer P. Magleby , John F. Marshall , W. Douglas Stout , Carl D. Sorensen , Ryan W. Warnick , Lee Baroldy , Lisa Cloward , David S. Bent , Adam Gaglione , Robert Cvetko , Aaron T. Schellenberg
IPC分类号： B65B130
CPC分类号： B67D7/344 , B67D7/0401 , B67D2007/0417 , B67D2007/0419 , B67D2007/0436 , B67D2007/0463 , B67D2007/0473 , B67D2007/0474
摘要： An automatic fueling system includes a pump having a telescoping arm capable of placement in three-dimensional space, a flexibly mounted nozzle on the end of the arm and a docking cone to mate with the fuel port on a vehicle. A camera provides a view of the side of the vehicle on a monitor with guides visible to the operator of the vehicle to assist in locating the vehicle within range of the pump. A light and a camera located adjacent to the nozzle are used to recognize retro-reflective light from an annular target about the intake port. Multiple approximations of the distance and location of the intake port are made with the nozzle moving closer to mating with the intake port. A data link is provided through the mated nozzle with a keypad accessible by the vehicle operator. The vehicle includes a control actuator which selectively couples actuator cables associated with the fuel door and the fuel inlet valve with the emergency brake cable to engage the emergency brake, open the fuel door and open the inlet valve. A vacuum system on an evaporation canister insures that vapor is drawn from the fuel tank as it is being displaced by incoming fuel.
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公开(公告)号：US4743917A
公开(公告)日：1988-05-10
申请号：US779259
申请日：1985-09-23
CPC分类号： H01Q1/087
摘要： A portable roll-out antenna system which forms a compact, transportable assembly when not being used. The roll-out antenna system is provided with flexible antenna elements which are individually wound onto reels for storage and transportation, and rolled out for use as an efficient antenna system. Each pair of antenna elements is connected to a balun for proper connection to unbalanced connecting cables. The baluns are housed in an end-cap assembly upon which are mounted the antenna element reels when the antenna system is not being used. A power splitter allows more than one connecting cable to be electrically coupled to a remote transmitter/receiver by way of a transmission line. The power splitter is housed in a center reel assembly which is provided with a component to lockably receive part of the end-cap assembly upon which is mounted the antenna-element reels, thus holding the antenna-element reels together and forming a compact, transportable assembly.
摘要翻译： 便携式推出天线系统，在不使用时形成紧凑的可运输组件。 推出天线系统设置有柔性天线元件，其单独地缠绕在用于存储和运输的卷轴上，并且被推出用作高效天线系统。 每对天线元件连接到平衡 - 不平衡转换器，以正确连接到不平衡连接电缆。 当不使用天线系统时，平衡 - 不平衡变压器被安装在端盖组合件中，天线元件盘上安装有天线元件。 功率分配器允许多个连接电缆通过传输线电耦合到远程发射器/接收器。 功率分配器容纳在中心卷轴组件中，该中心卷轴组件设置有可锁定地容纳端部组件的一部分的部件，在其上安装天线元件卷轴，从而将天线元件卷轴保持在一起并形成紧凑的，可运输的 部件。
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公开(公告)号：US6024137A
公开(公告)日：2000-02-15
申请号：US25684
申请日：1998-02-18
申请人： Rudolph A. Strnad , Spencer P. Magleby , John F. Marshall , W. Douglas Stout , Carl D. Sorensen , Ryan W. Warnick , Lee Baroldy , Lisa Cloward , David S. Bent , Adam Gaglione , Robert Cvetko , Aaron T. Schellenberg
发明人： Rudolph A. Strnad , Spencer P. Magleby , John F. Marshall , W. Douglas Stout , Carl D. Sorensen , Ryan W. Warnick , Lee Baroldy , Lisa Cloward , David S. Bent , Adam Gaglione , Robert Cvetko , Aaron T. Schellenberg
CPC分类号： B67D7/0401 , B67D7/344 , B67D2007/0417 , B67D2007/0419 , B67D2007/0436 , B67D2007/0463 , B67D2007/0473 , B67D2007/0474
摘要： An automatic fueling system includes a pump having a telescoping arm capable of placement in three-dimensional space, a flexibly mounted nozzle on the end of the arm and a docking cone to mate with the fuel port on a vehicle. A camera provides a view of the side of the vehicle on a monitor with guides visible to the operator of the vehicle to assist in locating the vehicle within range of the pump. A light and a camera located adjacent to the nozzle are used to recognize retro-reflective light from an annular target about the intake port. Multiple approximations of the distance and location of the intake port are made with the nozzle moving closer to mating with the intake port. A data link is provided through the mated nozzle with a keypad accessible by the vehicle operator. The vehicle includes a control actuator which selectively couples actuator cables associated with the fuel door and the fuel inlet valve with the emergency brake cable to engage the emergency brake, open the fuel door and open the inlet valve. A vacuum system on an evaporation canister insures that vapor is drawn from the fuel tank as it is being displaced by incoming fuel.
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6.发明授权Rationally-designed anti-αβν6 integrin antibody MFEVP1 and variants thereof, method of making such antibody and the use thereof in treating and diagnosis of disease 有权合理设计的抗α＆bgr＆amp; 6整联蛋白抗体MFEVP1及其变体，制备此类抗体的方法及其在治疗和诊断疾病中的应用公开(公告)号：US09050321B2
公开(公告)日：2015-06-09
申请号：US12680320
申请日：2008-09-26
申请人： Kerry Chester , Heide Kogelberg , John F. Marshall
发明人： Kerry Chester , Heide Kogelberg , John F. Marshall
CPC分类号： C07K16/2839 , A61K39/39541 , A61K39/39558 , C07K16/3007 , C07K2317/24 , C07K2317/31 , C07K2317/565 , C07K2317/622 , C07K2317/77 , C07K2318/10 , C07K2319/00
摘要： The present invention relates to antibodies that are obtained by inserting an amino acid sequence capable of binding to a target into the complementarity determining region (CDR) of a parent antibody. The antibody thus obtained has a new binding specificity. For example, the antibodies of the present invention are able to bind to the target, such as αvβ6 integrin, while retaining one or more of the useful properties of the parent antibody.
摘要翻译： 本发明涉及通过将能够与靶标结合的氨基酸序列插入母体抗体的互补决定区（CDR）而获得的抗体。 由此获得的抗体具有新的结合特异性。 例如，本发明的抗体能够结合靶，例如αv＆bgr6整联蛋白，同时保留亲本抗体的一个或多个有用特性。
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公开(公告)号：US20110053254A1
公开(公告)日：2011-03-03
申请号：US12680320
申请日：2008-09-26
申请人： Kerry Chester , John F. Marshall , Heide Kogelberg
发明人： Kerry Chester , John F. Marshall , Heide Kogelberg
CPC分类号： C07K16/2839 , A61K39/39541 , A61K39/39558 , C07K16/3007 , C07K2317/24 , C07K2317/31 , C07K2317/565 , C07K2317/622 , C07K2317/77 , C07K2318/10 , C07K2319/00
摘要： The invention relates to materials and methods for modifying the binding of antibodies, and more particularly to antibodies that are obtainable by inserting an amino acid sequence capable of binding to a target into a complementarity determining region of a parent antibody so that the antibody thus obtained is capable of binding to the target. The invention further relates to the uses of the antibodies for therapy, diagnosis or imaging, and to methods of producing the antibodies.
摘要翻译： 本发明涉及用于修饰抗体结合的材料和方法，更具体地说涉及通过将能够与靶标结合的氨基酸序列插入母体抗体的互补决定区域而得到的抗体，从而得到的抗体为 能够绑定到目标。 本发明还涉及抗体用于治疗，诊断或成像以及产生抗体的方法。
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公开(公告)号：US20090123370A1
公开(公告)日：2009-05-14
申请号：US12088998
申请日：2006-10-03
IPC分类号： A61K51/08 , C07K14/00 , C12N15/85 , C07K14/435 , A61P35/00 , A61P11/00 , A61P17/00 , A61P43/00 , A61K38/17 , C12N15/12 , A61K38/12
CPC分类号： C07K7/06 , A61K49/00 , C07K7/08 , C07K2319/00
摘要： AVβ6 peptide ligands, functional variants thereof and their nucleic acids encoding them are disclosed with their uses in the treatment and imaging of AVβ6 mediated diseases.
摘要翻译： 公开了其用于治疗和成像AVβ6介导的疾病的AVβ6肽配体及其功能变体及其编码它们的核酸。
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公开(公告)号：USD280623S
公开(公告)日：1985-09-17
申请号：US498766
申请日：1983-05-27
申请人： John F. Marshall
设计人： John F. Marshall
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公开(公告)号：US08383593B2
公开(公告)日：2013-02-26
申请号：US12088998
申请日：2006-10-03
IPC分类号： A61K38/48
CPC分类号： C07K7/06 , A61K49/00 , C07K7/08 , C07K2319/00
摘要： AVβ6 peptide ligands, functional variants thereof and their nucleic acids encoding them are disclosed with their uses in the treatment and imaging of AVβ6 mediated diseases.
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