公开(公告)号：US20230152398A1

公开(公告)日：2023-05-18

申请号：US17916703

申请日：2021-04-07

Applicant: North Carolina State University

Inventor： Thomas THEIS ,  Milad ABOLHASANI ,  Patrick TOMHON ,  Sören LEHMKUHL ,  Suyong HAN

IPC: G01R33/28 ,  G01R33/46

CPC classification number: G01R33/282 ,  G01R33/46

Abstract: In one aspect, the disclosure relates to a compact membrane reactor for parahydrogen induced hyperpolarization, the reactor including an inner tube constructed of a semipermeable membrane, an outer tube surrounding the inner tube, and a means for controlling the magnetic field surrounding the outer tube. In some aspects, multiple compact membrane reactors can be arranged in parallel. In other aspects, the compact membrane reactor is equipped with a mechanism for magnetic field control. Also disclosed are fluid handling systems and sample preparation systems comprising the compact membrane reactors disclosed herein. The compact membrane reactor can be operated in a batch mode, a stopped-flow mode, or a continuous flow mode and can be configured to work with existing NMR spectrometers and MRI instruments.