公开(公告)号：US11597733B2

公开(公告)日：2023-03-07

申请号：US17076126

申请日：2020-10-21

Applicant: Novartis AG

Inventor： Nicole Alice Blaquiere ,  Richard Yichong Huang ,  Thomas Martin Kirrane, Jr. ,  Andreas Kordikowski ,  Anne-Catherine Mata ,  Christopher Ronald Sarko ,  Benjamin Robert Taft ,  Grace Lamprecht Waldron ,  Fumiaki Yokokawa ,  Tingying Zhu

IPC: C07D513/04 ,  C07D519/00 ,  A61K31/4545 ,  A61K31/433 ,  A61K31/496 ,  A61K45/06 ,  A61K31/4439 ,  A61K31/5386 ,  A61K31/438 ,  A61K31/5355 ,  A61K31/499 ,  A61K31/454

Abstract: The present invention provides a compound of formula (Ia) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, solid forms, combinations of pharmacologically active agents, pharmaceutical compositions and methods of using such compounds and solid forms thereof to treat or prevent parasitic diseases, for example malaria.

公开(公告)号：US20210115065A1

公开(公告)日：2021-04-22

申请号：US17076126

申请日：2020-10-21

Applicant: Novartis AG

Inventor： Nicole Alice Blaquiere ,  Richard Yichong Huang ,  Thomas Martin Kirrane, JR. ,  Andreas Kordikowski ,  Anne-Catherine Mata ,  Christopher Ronald Sarko ,  Benjamin Robert Taft ,  Grace Lamprecht Waldron ,  Fumiaki Yokokawa ,  Tingying Zhu

IPC: C07D513/04 ,  C07D519/00 ,  A61K31/4545 ,  A61K31/433 ,  A61K31/496 ,  A61K31/454 ,  A61K31/4439 ,  A61K31/5386 ,  A61K31/438 ,  A61K31/5355 ,  A61K31/499 ,  A61K45/06

Abstract: The present invention provides a compound of formula (Ia) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, solid forms, combinations of pharmacologically active agents, pharmaceutical compositions and methods of using such compounds and solid forms thereof to treat or prevent parasitic diseases, for example malaria.