公开(公告)号：US10029994B2

公开(公告)日：2018-07-24

申请号：US15728351

申请日：2017-10-09

Applicant: Novartis AG

Inventor： Jiping Fu ,  Xianming Jin ,  Subramanian Karur ,  Guillaume Lapointe ,  Ann Marie Madera ,  Zachary Kevin Sweeney

IPC: C07D261/08 ,  C07D413/12 ,  C07D413/06 ,  A61K31/422 ,  A61K45/06 ,  A61K31/42

Abstract: This invention pertains generally to compounds of Formula I as described herein and compositions containing such compounds, as well as methods of using such compounds to treat bacterial infections. In certain aspects, the invention provides methods and compositions comprising these compounds for treating infections caused by Gram-negative bacteria.

公开(公告)号：US09815804B2

公开(公告)日：2017-11-14

申请号：US15375560

申请日：2016-12-12

Applicant: Novartis AG

Inventor： Jiping Fu ,  Xianming Jin ,  Subramanian Karur ,  Guillaume Lapointe ,  Ann Marie Madera ,  Zachary Kevin Sweeney

IPC: C07D261/08 ,  A61K31/42 ,  A61K45/06 ,  C07D413/12 ,  A61K31/422 ,  C07D413/06

CPC classification number: C07D261/08 ,  A61K31/42 ,  A61K31/422 ,  A61K45/06 ,  C07D413/06 ,  C07D413/12 ,  Y02A50/473 ,  Y02A50/475 ,  Y02A50/478 ,  Y02A50/481 ,  A61K2300/00

Abstract: This invention pertains generally to compounds of Formula I as described herein and compositions containing such compounds, as well as methods of using such compounds to treat bacterial infections. In certain aspects, the invention provides methods and compositions comprising these compounds for treating infections caused by Gram-negative bacteria.