公开(公告)号：US09751876B2

公开(公告)日：2017-09-05

申请号：US14511044

申请日：2014-10-09

Applicant: Novartis AG

Inventor： Ian Bruce ,  Sylvie Chamoin ,  Stephen Paul Collingwood ,  Pascal Furet ,  Vikki Furminger ,  Diana Janus ,  Sarah Lewis ,  Jon Christopher Loren ,  Valentina Molteni ,  Alex Michael Saunders ,  Duncan Shaw ,  Lilya Sviridenko ,  Christopher Thomson ,  Ryan West ,  Vince Yeh

IPC: C07D471/04 ,  A61K31/444 ,  A61K31/4545 ,  A61K31/496 ,  A61K31/5377 ,  A61K45/06 ,  A61K31/4745

CPC classification number: C07D471/04 ,  A61K31/444 ,  A61K31/4545 ,  A61K31/4745 ,  A61K31/496 ,  A61K31/5377 ,  A61K45/06

Abstract: Bicyclic heterocyclic derivatives of formula I useful in inhibiting PDGF receptor mediated biological activity. wherein A is and R1, R1a, R2, R3, R4, R5, R6 and X are as defined herein.