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公开(公告)号：US10041052B2
公开(公告)日：2018-08-07
申请号：US15249856
申请日：2016-08-29
Applicant: Novozymes A/S
Inventor： Leonardo De Maria , Carsten Andersen , Lars Kobberoee Skov , Mikael Blom Soerensen
IPC: C12N9/16 , A23K20/189
Abstract: The present invention relates to a phytase which has at least 74% identity to a phytase derived from Citrobacter braakii and comprises at least one alteration as compared to this phytase. These phytase variants have amended, preferably improved, properties, such as thermostability, temperature profile, pH profile, specific activity, performance in animal feed, reduced protease sensibility, and/or an amended glycosylation pattern. The invention also relates to DNA encoding these phytases, methods of their production, as well as the use thereof, e.g., in animal feed and animal feed additives.
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Patent Agency Ranking
公开(公告)号：US20150024084A1
公开(公告)日：2015-01-22
申请号：US14504517
申请日：2014-10-02
Applicant: NOVOZYMES A/S
Inventor： Leonardo De Maria , Carsten Andersen , Lars Kobberoee Skov , Mikael Blom Soerensen
CPC classification number: C12N9/16 , A23K20/189 , C12Y301/03
Abstract: The present invention relates to a phytase which has at least 74% identity to a phytase derived from Citrobacter braakii and comprises at least one alteration as compared to this phytase. These phytase variants have amended, preferably improved, properties, such as thermostability, temperature profile, pH profile, specific activity, performance in animal feed, reduced protease sensitiliby, and/or an amended glycosylation pattern. The invention also relates to DNA encoding these phytases, methods of their production, as well as the use thereof, e.g., in animal feed and animal feed additives.
Abstract translation: 本发明涉及一种植酸酶，其与来自柠檬酸杆菌的植酸酶具有至少74％的同一性，并且与该植酸酶相比包含至少一个改变。 这些植酸酶变体具有修饰，优选改进的性质，例如热稳定性，温度曲线，pH曲线，比活性，动物饲料中的性能，降低的蛋白酶敏感性和/或修饰的糖基化模式。 本发明还涉及编码这些植酸酶的DNA，其生产方法及其用途，例如在动物饲料和动物饲料添加剂中。
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公开(公告)号：US20130224332A1
公开(公告)日：2013-08-29
申请号：US13874954
申请日：2013-05-01
Applicant: Novozymes A/S
Inventor： Leonardo De Maria , Carsten Andersen , Lars Kobberoee Skov , Mikael Blom Soerensen
CPC classification number: C12N9/16 , A23K20/189 , C12Y301/03
Abstract: The present invention relates to a phytase which has at least 74% identity to a phytase derived from Citrobacter braakii and comprises at least one alteration as compared to this phytase. These phytase variants have amended, preferably improved, properties, such as thermostability, temperature profile, pH profile, specific activity, performance in animal feed, reduced protease sensitiliby, and/or an amended glycosylation pattern. The invention also relates to DNA encoding these phytases, methods of their production, as well as the use thereof, e.g. in animal feed and animal feed additives.
Abstract translation: 本发明涉及一种植酸酶，其与来自柠檬酸杆菌的植酸酶具有至少74％的同一性，并且与该植酸酶相比包含至少一个改变。 这些植酸酶变体具有修饰，优选改进的性质，例如热稳定性，温度曲线，pH曲线，比活性，动物饲料中的性能，降低的蛋白酶敏感性和/或修饰的糖基化模式。 本发明还涉及编码这些植酸酶的DNA，其生产方法及其用途，例如， 在动物饲料和动物饲料添加剂中。
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公开(公告)号：US20160362666A1
公开(公告)日：2016-12-15
申请号：US15249856
申请日：2016-08-29
Applicant: Novozymes A/S
Inventor： Leonardo De Maria , Carsten Andersen , Lars Kobberoee Skov , Mikael Blom Soerensen
IPC: C12N9/16 , A23K20/189
CPC classification number: C12N9/16 , A23K20/189 , C12Y301/03
Abstract: The present invention relates to a phytase which has at least 74% identity to a phytase derived from Citrobacter braakii and comprises at least one alteration as compared to this phytase. These phytase variants have amended, preferably improved, properties, such as thermostability, temperature profile, pH profile, specific activity, performance in animal feed, reduced protease sensibility, and/or an amended glycosylation pattern. The invention also relates to DNA encoding these phytases, methods of their production, as well as the use thereof, e.g., in animal feed and animal feed additives.
Abstract translation: 本发明涉及一种植酸酶，其与来自柠檬酸杆菌的植酸酶具有至少74％的同一性，并且与该植酸酶相比包含至少一个改变。 这些植酸酶变体具有修饰，优选改进的性质，例如热稳定性，温度曲线，pH曲线，比活性，动物饲料中的性能，降低的蛋白酶敏感性和/或修饰的糖基化模式。 本发明还涉及编码这些植酸酶的DNA，其生产方法及其用途，例如在动物饲料和动物饲料添加剂中。
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公开(公告)号：US09451783B2
公开(公告)日：2016-09-27
申请号：US14504517
申请日：2014-10-02
Applicant: Novozymes A/S
Inventor： Leonardo De Maria , Carsten Andersen , Lars Kobberoee Skov , Mikael Blom Soerensen
CPC classification number: C12N9/16 , A23K20/189 , C12Y301/03
Abstract: The present invention relates to a phytase which has at least 74% identity to a phytase derived from Citrobacter braakii and comprises at least one alteration as compared to this phytase. These phytase variants have amended, preferably improved, properties, such as thermostability, temperature profile, pH profile, specific activity, performance in animal feed, reduced protease sensitiliby, and/or an amended glycosylation pattern. The invention also relates to DNA encoding these phytases, methods of their production, as well as the use thereof, e.g., in animal feed and animal feed additives.
Abstract translation: 本发明涉及一种植酸酶，其与来自柠檬酸杆菌的植酸酶具有至少74％的同一性，并且与该植酸酶相比包含至少一个改变。 这些植酸酶变体具有修饰，优选改进的性质，例如热稳定性，温度曲线，pH曲线，比活性，动物饲料中的性能，降低的蛋白酶敏感性和/或修饰的糖基化模式。 本发明还涉及编码这些植酸酶的DNA，其生产方法及其用途，例如在动物饲料和动物饲料添加剂中。
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公开(公告)号：US08877471B2
公开(公告)日：2014-11-04
申请号：US13874954
申请日：2013-05-01
Applicant: Novozymes A/S
Inventor： Leonardo De Maria , Carsten Andersen , Lars Kobberoee Skov , Mikael Blom Soerensen
CPC classification number: C12N9/16 , A23K20/189 , C12Y301/03
Abstract: The present invention relates to a phytase which has at least 74% identity to a phytase derived from Citrobacter braakii and comprises at least one alteration as compared to this phytase. These phytase variants have amended, preferably improved, properties, such as thermostability, temperature profile, pH profile, specific activity, performance in animal feed, reduced protease sensitiliby, and/or an amended glycosylation pattern. The invention also relates to DNA encoding these phytases, methods of their production, as well as the use thereof, e.g. in animal feed and animal feed additives.
Abstract translation: 本发明涉及一种植酸酶，其与来自柠檬酸杆菌的植酸酶具有至少74％的同一性，并且与该植酸酶相比包含至少一个改变。 这些植酸酶变体具有修饰，优选改进的性质，例如热稳定性，温度曲线，pH曲线，比活性，动物饲料中的性能，降低的蛋白酶敏感性和/或修饰的糖基化模式。 本发明还涉及编码这些植酸酶的DNA，其生产方法及其用途，例如， 在动物饲料和动物饲料添加剂中。
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