公开(公告)号：US10168518B2

公开(公告)日：2019-01-01

申请号：US15436742

申请日：2017-02-17

Applicant: OLYMPUS CORPORATION

Inventor： Yusuke Amano ,  Susumu Honda

IPC: G02B21/00 ,  G02B27/00 ,  G02B21/08 ,  G02B21/26

Abstract: Provided is a laser scanning microscope including a stage on which a sample is placed, an objective lens that is disposed below the stage and that focuses laser light from a light source onto the sample, a scanner that scans the laser light focused by the objective lens over the sample, a condenser lens disposed opposite the objective lens with the stage interposed therebetween, and a light blocking cover that is disposed in an optical path between the condenser lens and the stage and that blocks external light entering the objective lens or the condenser lens from above the sample via the stage.

公开(公告)号：US09568357B2

公开(公告)日：2017-02-14

申请号：US14539760

申请日：2014-11-12

Applicant: OLYMPUS CORPORATION

Inventor： Yusuke Amano ,  Masaharu Tomioka

IPC: G02B21/00 ,  G01J1/04 ,  G02B27/14

CPC classification number: G01J1/0407 ,  G02B21/0032 ,  G02B21/0064 ,  G02B21/008 ,  G02B27/145

Abstract: The number of detection channels of detecting sections is increased and the detecting sections are replaced easily and at low cost while suppressing loss in the quantity of returning light. Provided is a detection unit (5A) including a detector entrance port (75A) through which light in a predetermined optical form enters, a detector (57A) that detects at least a portion of the light entering through the detector entrance port (75A), and a detector exit port (65A) through which at least another portion of the light entering through the detector entrance port (75A) can exit in the same optical form.

Abstract translation: 检测部分的检测通道的数量增加，并且容易且低成本地更换检测部分，同时抑制返回光量的损失。 提供了一种检测单元（5A），其包括检测器入口（75A），预定光学形式的光进入该检测器入口端口，检测器（57A），其检测通过检测器入口（75A）进入的光的至少一部分; 和检测器出口（65A），通过检测器入口（75A）进入的光的至少另一部分可以通过该检测器出口端口以相同的光学形式退出。

公开(公告)号：US09372330B2

公开(公告)日：2016-06-21

申请号：US14226537

申请日：2014-03-26

Applicant: OLYMPUS CORPORATION

Inventor： Yusuke Amano ,  Masayoshi Karasawa

IPC: G02B21/00 ,  G01N21/64

CPC classification number: G02B21/0044 ,  G01N21/648 ,  G02B21/0076 ,  G02B21/0088

Abstract: An inverted microscope system includes an objective lens holding unit that holds an objective lens configured to collect at least observation light from a specimen, a tube lens configured to form an image using the observation light collected by the objective lens, a total internal reflection fluorescence microscopy optical system provided between the objective lens and the tube lens and configured to observe the observation light from the specimen using a total reflection illumination, and a disk scanning confocal optical system including a rotary disk on which a confocal opening is formed, the confocal opening being placed at a position substantially conjugate to a focus position of the objective lens. A relative distance between the focus position of the objective lens and the substantially conjugate position is changeable along an optical path of the observation light.

Abstract translation: 倒置显微镜系统包括：物镜保持单元，其保持配置成至少收集来自观察者的观察光的物镜;配置为使用由所述物镜收集的观察光形成图像的管透镜，全内反射荧光显微镜 光学系统，设置在物镜和管透镜之间，并配置为使用全反射照明观察来自样本的观察光;以及盘式扫描共焦光学系统，包括形成有共焦开口的旋转盘，共焦开口为 放置在与物镜的焦点位置基本共轭的位置处。 物镜的焦点位置与基本共轭位置之间的相对距离可沿着观察光的光路改变。

公开(公告)号：US09494780B2

公开(公告)日：2016-11-15

申请号：US13851921

申请日：2013-03-27

Applicant: OLYMPUS CORPORATION

Inventor： Akihiro Kitahara ,  Hironori Utsugi ,  Yusuke Amano

IPC: G02B21/00 ,  G02B21/24

CPC classification number: G02B21/0088 ,  G02B21/24

Abstract: An inverted microscope includes an imaging lens configured to form an image of light which passes through an objective lens from a specimen, and a microscope main body in which a plurality of optical devices are configured to be arranged between the objective lens and the imaging lens in a direction of an optical axis of the objective lens and which includes therein a plurality of installation units that allow the plurality of optical devices to be fixed independently of one another. Each of the plurality of installation units includes an abutting reference surface on which any one of the plurality of optical devices is configured to be abutted. A plurality of abutting reference surfaces of the plurality of the installation units are shifted from one another in a direction perpendicular to the optical axis of the objective lens.

Abstract translation: 倒置显微镜包括：成像透镜，被配置为形成从样本穿过物镜的光的图像;以及显微镜主体，其中多个光学器件被配置为布置在物镜和成像透镜之间 物镜的光轴的方向，并且其中包括允许多个光学装置彼此独立地固定的多个安装单元。 所述多个安装单元中的每一个包括邻接的基准面，所述多个光学装置中的任一个配置在所述对准基准面上。 多个安装单元的多个邻接的基准面在与物镜的光轴垂直的方向上彼此偏移。

公开(公告)号：US09405113B2

公开(公告)日：2016-08-02

申请号：US13926934

申请日：2013-06-25

Applicant: OLYMPUS CORPORATION

Inventor： Yusuke Amano ,  Takayoshi Kamomae ,  Yuichi Kataoka

IPC: G02B21/06 ,  G02B21/26

CPC classification number: G02B21/26

Abstract: A microscope focusing mechanism includes a fixing part attached to a microscope main body, a fixing-side guide member attached to the fixing part, a plate-shaped base part that supports at least one of a stage for placing a specimen and a revolver to which multiple objective lenses are detachably attached, a moving-side guide member that is fixed to the base part, that is connected to the fixing-side guide member, and that is movable in a direction of an optical axis of one of the objective lenses, and a plate member that is arranged on a side of the base part opposite to a side where the moving-side guide member is arranged. A linear expansion coefficient of a material of each of the moving-side guide member and the plate member differs from a linear expansion coefficient of a material of the base part.

Abstract translation: 显微镜聚焦机构包括安装在显微镜主体上的固定部件，安装在固定部件上的固定侧引导部件，支撑用于放置试样的台架和左轮手枪中的至少一个的板状基部， 多个物镜是可拆卸地安装的，移动侧引导件固定到基座部分，该导向件连接到固定侧引导件，并且可沿着一个物镜的光轴方向移动， 以及板构件，其布置在所述基部的与所述可动侧引导构件的一侧相对的一侧。 移动侧引导构件和板构件的材料的线膨胀系数与基部的材料的线膨胀系数不同。