Identification of patient sub-cohorts and corresponding quantitative definitions of subtypes as a classification system for medical conditions

    公开(公告)号:US11862346B1

    公开(公告)日:2024-01-02

    申请号:US16724264

    申请日:2019-12-21

    申请人: OM1, Inc.

    IPC分类号: G16H50/70 G16H10/60

    CPC分类号: G16H50/70 G16H10/60

    摘要: A classification method and system for medical conditions based on the concept of subtypes, which are classes of patients whose medical fact patterns as analyzed in an N-dimensional space places them closer to other patients belonging to the same subtype than to patients who belong to different subtypes and, who share similar likelihood of certain specified outcomes. A computer system processes patient data for a plurality of patients from a set of patients called a cohort. The computer system processes the patient data for the cohort to group patients into sub-cohorts of similar patients, i.e., each sub-cohort includes patients who have similar medical fact patterns in their patient data. Patients in different sub-cohorts generally, but not necessarily, have significant differences in their patient data. The computer system generates quantitative definitions, describing the patients in the sub-cohorts.

    Health care information system providing additional data fields in patient data

    公开(公告)号:US11594310B1

    公开(公告)日:2023-02-28

    申请号:US15465542

    申请日:2017-03-21

    申请人: OM1, Inc.

    IPC分类号: H04L67/01 G16H10/60 G06N20/00

    摘要: Health care information for multiple patients is processed to classify patients into categories. Additional data fields related to a category in which a patient is classified are added to the patient record. These data fields are populated in part by automatically processing the existing patient data. Such automatic processing can result in a probability that the underlying data supports having a particular value stored in one of the added data fields, and this probability also can be stored. Over time, additional data can be obtained from patients, caregivers and other sources, for structured data fields based on data entry forms for patient reported outcomes, caregiver reported outcomes, events of interest, survival and resource utilization. A set of factor scores is computed for each patient, for each category in which the patient is classified. An outcome score is computed for each patient for each category in which the patient is classified, using an outcome function defined for that category, as a weighted function of one or more of the factor scores. The outcome function for a category is standardized across all patients classified in that category.

    IDENTIFICATION OF PATIENT SUB-COHORTS AND CORRESPONDING QUANTITATIVE DEFINITIONS OF SUBTYPES AS A CLASSIFICATION SYSTEM FOR MEDICAL CONDITIONS

    公开(公告)号:US20240096500A1

    公开(公告)日:2024-03-21

    申请号:US18520664

    申请日:2023-11-28

    申请人: OM1, Inc.

    IPC分类号: G16H50/70 G16H10/60

    CPC分类号: G16H50/70 G16H10/60

    摘要: A classification method and system for medical conditions based on the concept of subtypes, which are classes of patients whose medical fact patterns as analyzed in an N-dimensional space places them closer to other patients belonging to the same subtype than to patients who belong to different subtypes and, who share similar likelihood of certain specified outcomes. A computer system processes patient data for a plurality of patients from a set of patients called a cohort. The computer system processes the patient data for the cohort to group patients into sub-cohorts of similar patients, i.e., each sub-cohort includes patients who have similar medical fact patterns in their patient data. Patients in different sub-cohorts generally, but not necessarily, have significant differences in their patient data. The computer system generates quantitative definitions, describing the patients in the sub-cohorts.

    INFORMATION SYSTEM PROVIDING EXPLANATION OF MODELS

    公开(公告)号:US20220148695A1

    公开(公告)日:2022-05-12

    申请号:US17573725

    申请日:2022-01-12

    申请人: OM1, Inc.

    IPC分类号: G16H10/60 G06N5/02 G06N20/00

    摘要: A health care information system generates information that describes how different inputs to a model affect the output of the model, by creating a localized model for a given entity, and determining how the output of the localized model for the given entity changes in response to different inputs. The computer system builds the localized model for a given entity based on the model and on data values for the given entity. The computer system inputs one or more different data values for selected input features of the localized model, while data values for the remaining input features of the localized model are fixed to data values for the given entity, and obtains corresponding outputs from the localized model. The results from this localized model for the given entity indicate which of the selected input features have the most impact on the output of the model for that entity.

    Health care information system providing additional data fields in patient data

    公开(公告)号:US12057204B2

    公开(公告)日:2024-08-06

    申请号:US18169363

    申请日:2023-02-15

    申请人: OM1, Inc.

    摘要: Health care information for multiple patients is processed to classify patients into categories. Additional data fields related to a category in which a patient is classified are added to the patient record. These data fields are populated in part by automatically processing the existing patient data. Such automatic processing can result in a probability that the underlying data supports having a particular value stored in one of the added data fields, and this probability also can be stored. Over time, additional data can be obtained from patients, caregivers and other sources, for structured data fields based on data entry forms for patient reported outcomes, caregiver reported outcomes, events of interest, survival and resource utilization. A set of factor scores is computed for each patient, for each category in which the patient is classified. An outcome score is computed for each patient for each category in which the patient is classified, using an outcome function defined for that category, as a weighted function of one or more of the factor scores. The outcome function for a category is standardized across all patients classified in that category.

    IDENTIFICATION OF PATIENT SUB-COHORTS AND CORRESPONDING QUANTITATIVE DEFINITIONS OF SUBTYPES AS A CLASSIFICATION SYSTEM FOR MEDICAL CONDITIONS

    公开(公告)号:US20240153647A1

    公开(公告)日:2024-05-09

    申请号:US18414296

    申请日:2024-01-16

    申请人: OM1, Inc.

    IPC分类号: G16H50/70 G16H10/60

    CPC分类号: G16H50/70 G16H10/60

    摘要: A classification method and system for medical conditions based on the concept of subtypes, which are classes of patients whose medical fact patterns as analyzed in an N-dimensional space places them closer to other patients belonging to the same subtype than to patients who belong to different subtypes and, who share similar likelihood of certain specified outcomes. A computer system processes patient data for a plurality of patients from a set of patients called a cohort. The computer system processes the patient data for the cohort to group patients into sub-cohorts of similar patients, i.e., each sub-cohort includes patients who have similar medical fact patterns in their patient data. Patients in different sub-cohorts generally, but not necessarily, have significant differences in their patient data. The computer system generates quantitative definitions, describing the patients in the sub-cohorts.

    HEALTH CARE INFORMATION SYSTEM PROVIDING ADDITIONAL DATA FIELDS IN PATIENT DATA

    公开(公告)号:US20230197223A1

    公开(公告)日:2023-06-22

    申请号:US18169363

    申请日:2023-02-15

    申请人: OM1, Inc.

    IPC分类号: G16H10/60 G06F17/11 G06N20/00

    摘要: Health care information for multiple patients is processed to classify patients into categories. Additional data fields related to a category in which a patient is classified are added to the patient record. These data fields are populated in part by automatically processing the existing patient data. Such automatic processing can result in a probability that the underlying data supports having a particular value stored in one of the added data fields, and this probability also can be stored. Over time, additional data can be obtained from patients, caregivers and other sources, for structured data fields based on data entry forms for patient reported outcomes, caregiver reported outcomes, events of interest, survival and resource utilization. A set of factor scores is computed for each patient, for each category in which the patient is classified. An outcome score is computed for each patient for each category in which the patient is classified, using an outcome function defined for that category, as a weighted function of one or more of the factor scores. The outcome function for a category is standardized across all patients classified in that category.

    Information system providing explanation of models

    公开(公告)号:US11257574B1

    公开(公告)日:2022-02-22

    申请号:US15927766

    申请日:2018-03-21

    申请人: OM1, Inc.

    IPC分类号: G16H10/60 G06N5/02 G06N20/00

    摘要: A health care information system generates information that describes how different inputs to a model affect the output of the model, by creating a localized model for a given entity, and determining how the output of the localized model for the given entity changes in response to different inputs. The computer system builds the localized model for a given entity based on the model and on data values for the given entity. The computer system inputs one or more different data values for selected input features of the localized model, while data values for the remaining input features of the localized model are fixed to data values for the given entity, and obtains corresponding outputs from the localized model. The results from this localized model for the given entity indicate which of the selected input features have the most impact on the output of the model for that entity.