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公开(公告)号：US20230159588A1
公开(公告)日：2023-05-25
申请号：US18094167
申请日：2023-01-06
Applicant: ONCOTHERAPY SCIENCE, INC.
Inventor： SACHIKO YAMASHITA , TETSURO HIKICHI
Abstract: The present invention provides CDCA1-derived epitope peptides having the ability to induce cytotoxic T cells. The present invention further provides polynucleotides encoding the peptides, antigen-presenting cells presenting the peptides, and cytotoxic T cells targeting the peptides, as well as methods of inducing the antigen-presenting cells or CTLs. The present invention also provides compositions and pharmaceutical compositions containing them as an active ingredient. Further, the present invention provides methods of treating and/or preventing cancer, and/or preventing postoperative recurrence thereof, using the peptides, polynucleotides, antigen-presenting cells, cytotoxic T cells or pharmaceutical compositions of the present invention. Methods of inducing an immune response against cancer are also provided.
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Patent Agency Ranking
公开(公告)号：US20170333476A1
公开(公告)日：2017-11-23
申请号：US15501125
申请日：2015-07-31
Applicant: ONCOTHERAPY SCIENCE, INC.
Inventor： Takuya TSUNODA , RYUJI OSAWA , SACHIKO YAMASHITA , TOMOHISA WATANABE , TETSURO HIKICHI
Abstract: The present invention provides KOC1-derived epitope peptides having the ability to induce cytotoxic T cells. The present invention further provides polynucleotides encoding the peptides, antigen-presenting cells presenting the peptides, and cytotoxic T cells targeting the peptides, as well as methods of inducing the antigen-presenting cells or CTLs. The present invention also provides compositions and pharmaceutical compositions containing them as an active ingredient. Further, the present invention provides methods of treating and/or preventing cancer, and/or preventing postoperative recurrence thereof, using the peptides, polynucleotides, antigen-presenting cells, cytotoxic T cells or pharmaceutical compositions of the present invention. Methods of inducing an immune response against cancer are also provided.
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公开(公告)号：US20180079791A1
公开(公告)日：2018-03-22
申请号：US15500906
申请日：2015-07-31
Applicant: ONCOTHERAPY SCIENCE, INC.
Inventor： TAKUYA TSUNODA , RYUJI OSAWA , SACHIKO YAMASHITA , TOMOHISA WATANABE
IPC: C07K14/47 , C07K16/18 , G01N33/574 , A61K39/00 , G01N33/50
Abstract: The present invention provides CDCA1-derived epitope peptides having the ability to induce cytotoxic T cells. The present invention further provides polynucleotides encoding the peptides, antigen-presenting cells presenting the peptides, and cytotoxic T cells targeting the peptides, as well as methods of inducing the antigen-presenting cells or CTLs. The present invention also provides compositions and pharmaceutical compositions containing them as an active ingredient. Further, the present invention provides methods of treating and/or preventing cancer, and/or preventing postoperative recurrence thereof, using the peptides, polynucleotides, antigen-presenting cells, cytotoxic T cells or pharmaceutical compositions of the present invention. Methods of inducing an immune response against cancer are also provided.
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公开(公告)号：US20180042954A1
公开(公告)日：2018-02-15
申请号：US15500895
申请日：2015-07-31
Applicant: ONCOTHERAPY SCIENCE, INC.
Inventor： TAKUYA TSUNODA , RYUJI OSAWA , SACHIKO YAMASHITA , TOMOHISA WATANABE , TETSURO HIKICHI
Abstract: The present invention provides URLC10-derived epitope peptides having the ability to induce cytotoxic T cells. The present invention further provides polynucleotides encoding the peptides, antigen-presenting cells presenting the peptides, and cytotoxic T cells targeting the peptides, as well as methods of inducing the antigen-presenting cells or CTLs. The present invention also provides compositions and pharmaceutical compositions containing them as an active ingredient. Further, the present invention provides methods of treating and/or preventing cancer, and/or preventing postoperative recurrence thereof, using the peptides, polynucleotides, antigen-presenting cells, cytotoxic T cells or pharmaceutical compositions of the present invention. Methods of inducing an immune response against cancer are also provided.
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公开(公告)号：US20210371462A1
公开(公告)日：2021-12-02
申请号：US17264277
申请日：2019-08-01
Applicant: ONCOTHERAPY SCIENCE, INC.
Inventor： SACHIKO YAMASHITA , Tetsuro HIKICHI
Abstract: The present invention provides CDCA1-derived epitope peptides having the ability to induce cytotoxic T cells. The present invention further provides polynucleotides encoding the peptides, antigen-presenting cells presenting the peptides, and cytotoxic T cells targeting the peptides, as well as methods of inducing the antigen-presenting cells or CTLs. The present invention also provides compositions and pharmaceutical compositions containing them as an active ingredient. Further, the present invention provides methods of treating and/or preventing cancer, and/or preventing postoperative recurrence thereof, using the peptides, polynucleotides, antigen-presenting cells, cytotoxic T cells or pharmaceutical compositions of the present invention. Methods of inducing an immune response against cancer are also provided.
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公开(公告)号：US20200308224A1
公开(公告)日：2020-10-01
申请号：US16854586
申请日：2020-04-21
Applicant: ONCOTHERAPY SCIENCE, INC.
Inventor： SACHIKO YAMASHITA , TETSURO HIKICHI
IPC: C07K7/06 , A61K39/00 , C12N5/10 , C12N15/09 , A61K31/7088 , C07K7/08 , A61P35/00 , C07K16/18 , C12N5/0783
Abstract: The present invention provides DEPDC1-derived epitope peptides having the ability to induce cytotoxic T cells. The present invention further provides polynucleotides encoding the peptides, antigen-presenting cells presenting the peptides, and cytotoxic T cells targeting the peptides, as well as methods of inducing the antigen-presenting cells or CTLs. The present invention also provides compositions and pharmaceutical compositions containing them as an active ingredient. Further, the present invention provides methods of treating and/or preventing cancer, and/or preventing postoperative recurrence thereof, using the peptides, polynucleotides, antigen-presenting cells, cytotoxic T cells or pharmaceutical compositions of the present invention. Methods of inducing an immune response against cancer are also provided.
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