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公开(公告)号：US20200155596A1
公开(公告)日：2020-05-21
申请号：US16773487
申请日：2020-01-27
Applicant: ONCOTHERAPY SCIENCE, INC.
Inventor： Takuya TSUNODA , Ryuji OSAWA , Sachiko YAMASHITA , Tomohisa WATANABE , Tetsuro HIKICHI
IPC: A61K35/14 , C12N15/09 , C12N5/10 , C07K7/08 , C07K7/06 , C07K16/18 , A61K48/00 , A61K39/00 , A61K35/12
Abstract: The present invention provides KOC1-derived epitope peptides having the ability to induce cytotoxic T cells. The present invention further provides polynucleotides encoding the peptides, antigen-presenting cells presenting the peptides, and cytotoxic T cells targeting the peptides, as well as methods of inducing the antigen-presenting cells or CTLs. The present invention also provides compositions and pharmaceutical compositions containing them as an active ingredient. Further, the present invention provides methods of treating and/or preventing cancer, and/or preventing postoperative recurrence thereof, using the peptides, polynucleotides, antigen-presenting cells, cytotoxic T cells or pharmaceutical compositions of the present invention. Methods of inducing an immune response against cancer are also provided.
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公开(公告)号：US20180362581A1
公开(公告)日：2018-12-20
申请号：US15762480
申请日：2016-10-06
Applicant: OncoTherapy Science, Inc.
Inventor： Sachiko YAMASHITA , Tetsuro HIKICHI
Abstract: The present invention provides MPHOSPH1-derived epitope peptides having the ability to induce cytotoxic T cells. The present invention further provides polynucleotides encoding the peptides, antigen-presenting cells presenting the peptides, and cytotoxic T cells targeting the peptides, as well as methods of inducing the antigen-presenting cells or CTLs. The present invention also provides compositions and pharmaceutical compositions containing them as an active ingredient. Further, the present invention provides methods of treating and/or preventing cancer, and/or preventing postoperative recurrence thereof, using the peptides, polynucleotides, antigen-presenting cells, cytotoxic T cells or pharmaceutical compositions of the present invention. Methods of inducing an immune response against cancer are also provided.
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公开(公告)号：US20210371462A1
公开(公告)日：2021-12-02
申请号：US17264277
申请日：2019-08-01
Applicant: ONCOTHERAPY SCIENCE, INC.
Inventor： SACHIKO YAMASHITA , Tetsuro HIKICHI
Abstract: The present invention provides CDCA1-derived epitope peptides having the ability to induce cytotoxic T cells. The present invention further provides polynucleotides encoding the peptides, antigen-presenting cells presenting the peptides, and cytotoxic T cells targeting the peptides, as well as methods of inducing the antigen-presenting cells or CTLs. The present invention also provides compositions and pharmaceutical compositions containing them as an active ingredient. Further, the present invention provides methods of treating and/or preventing cancer, and/or preventing postoperative recurrence thereof, using the peptides, polynucleotides, antigen-presenting cells, cytotoxic T cells or pharmaceutical compositions of the present invention. Methods of inducing an immune response against cancer are also provided.
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公开(公告)号：US20180222941A1
公开(公告)日：2018-08-09
申请号：US15751406
申请日：2016-08-10
Applicant: OncoTherapy Science, Inc.
Inventor： Sachiko YAMASHITA , Tetsuro HIKICHI
IPC: C07K7/06 , A61P35/00 , C12N5/0783 , C07K16/18
Abstract: The present invention provides DEPDC1-derived epitope peptides having the ability to induce cytotoxic T cells. The present invention further provides polynucleotides encoding the peptides, antigen-presenting cells presenting the peptides, and cytotoxic T cells targeting the peptides, as well as methods of inducing the antigen-presenting cells or CTLs. The present invention also provides compositions and pharmaceutical compositions containing them as an active ingredient. Further, the present invention provides methods of treating and/or preventing cancer, and/or preventing postoperative recurrence thereof, using the peptides, polynucleotides, antigen-presenting cells, cytotoxic T cells or pharmaceutical compositions of the present invention. Methods of inducing an immune response against cancer are also provided.
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