公开(公告)号：US12131802B2

公开(公告)日：2024-10-29

申请号：US15443102

申请日：2017-02-27

申请人： OPKO Diagnostics, LLC ,  Oy Arctic Partners Ab

发明人： Andrew J. Vickers ,  Peter T. Scardino ,  Hans Lilja ,  Vincent Linder ,  David Steinmiller

IPC分类号： G16B20/00 ,  B01L3/00 ,  C12Q1/6886 ,  G01N33/543 ,  G01N33/574 ,  G01N33/68 ,  G16B40/00 ,  G16H10/40 ,  G16H50/20 ,  G16H50/30

CPC分类号： G16B20/00 ,  B01L3/502 ,  B01L3/502715 ,  B01L3/502761 ,  C12Q1/6886 ,  G01N33/54366 ,  G01N33/57434 ,  G01N33/6893 ,  G16B40/00 ,  G16H10/40 ,  G16H50/20 ,  G16H50/30 ,  B01L2300/0654 ,  B01L2300/0816 ,  B01L2300/087 ,  B01L2400/0487 ,  C12Q2600/112 ,  C12Q2600/158 ,  C12Q2600/16 ,  G01N2333/96455

摘要： Methods and apparatuses for predicting risk of prostate cancer and/or prostate gland volume are provided. More particularly, this disclosure relates to methods and apparatuses for providing the models and employing the models for predicting risk of prostate cancer and/or predicting prostate gland volume. The methods and apparatuses for predicting risk of prostate cancer and/or prostate gland volume are provided using, at least in part, information from a panel of kallikrein markers.

公开(公告)号：US20170091380A1

公开(公告)日：2017-03-30

申请号：US15197172

申请日：2016-06-29

申请人： OPKO Diagnostics, LLC ,  OY Arctic Partners Ab

发明人： Andrew J. Vickers ,  Peter T. Scardino ,  Hans Lilja ,  Vincent Linder ,  David Steinmiller

IPC分类号： G06F19/18 ,  C12Q1/68 ,  G01N33/543 ,  G06F19/00 ,  G06F19/24

CPC分类号： G16B20/00 ,  B01L3/502 ,  B01L3/502715 ,  B01L3/502761 ,  B01L2300/0654 ,  B01L2300/0816 ,  B01L2300/087 ,  B01L2400/0487 ,  C12Q1/6886 ,  C12Q2600/112 ,  C12Q2600/158 ,  C12Q2600/16 ,  G01N33/54366 ,  G01N33/57434 ,  G01N33/6893 ,  G01N2333/96455 ,  G16B40/00 ,  G16H10/40 ,  G16H50/20 ,  G16H50/30

摘要： Methods and apparatuses for conducting analyses are provided.

公开(公告)号：US09672329B2

公开(公告)日：2017-06-06

申请号：US13785058

申请日：2013-03-05

申请人： Oy Arctic Partners Ab ,  OPKO Diagnostics, LLC

发明人： Andrew J. Vickers ,  Peter T. Scardino ,  Hans Lilja ,  Vincent Linder ,  David Steinmiller

IPC分类号： G01N33/48 ,  G06F19/00 ,  G06F19/18 ,  G06F19/24 ,  B01L3/00 ,  G01N33/68 ,  G06G7/48

CPC分类号： G06F19/18 ,  B01L3/502 ,  B01L3/502715 ,  B01L3/502761 ,  B01L2300/0654 ,  B01L2300/0816 ,  B01L2300/087 ,  B01L2400/0487 ,  C12Q1/6886 ,  C12Q2600/112 ,  C12Q2600/158 ,  C12Q2600/16 ,  G01N33/54366 ,  G01N33/57434 ,  G01N33/6893 ,  G01N2333/96455 ,  G06F19/00 ,  G06F19/24 ,  G16H10/40 ,  G16H50/20 ,  G16H50/30

摘要： Methods and apparatuses for predicting risk of prostate cancer and/or prostate gland volume are provided. More particularly, this disclosure relates to methods and apparatuses for providing the models and employing the models for predicting risk of prostate cancer and/or predicting prostate gland volume. The methods and apparatuses for predicting risk of prostate cancer and/or prostate gland volume are provided using, at least in part, information from a panel of kallikrein markers.

公开(公告)号：US10672503B2

公开(公告)日：2020-06-02

申请号：US15197148

申请日：2016-06-29

申请人： OPKO Diagnostics, LLC ,  Oy Arctic Partners Ab

发明人： Andrew J. Vickers ,  Peter T. Scardino ,  Hans Lilja ,  Vincent Linder ,  David Steinmiller

IPC分类号： G01N33/48 ,  G16B20/00 ,  G16H10/40 ,  G16B40/00 ,  B01L3/00 ,  G01N33/68 ,  G16H50/30 ,  C12Q1/6886 ,  G01N33/543 ,  G16H50/20 ,  G01N33/574 ,  G06G7/58

摘要： Methods and apparatuses for conducting analyses are provided.

公开(公告)号：US20170168060A1

公开(公告)日：2017-06-15

申请号：US15443102

申请日：2017-02-27

申请人： OPKO Diagnostics, LLC ,  Oy Arctic Partners Ab

发明人： Andrew J. Vickers ,  Peter T. Scardino ,  Hans Lilja ,  Vincent Linder ,  David Steinmiller

IPC分类号： G01N33/574 ,  G06F19/24 ,  B01L3/00 ,  G06F19/00

CPC分类号： G16B20/00 ,  B01L3/502 ,  B01L3/502715 ,  B01L3/502761 ,  B01L2300/0654 ,  B01L2300/0816 ,  B01L2300/087 ,  B01L2400/0487 ,  C12Q1/6886 ,  C12Q2600/112 ,  C12Q2600/158 ,  C12Q2600/16 ,  G01N33/54366 ,  G01N33/57434 ,  G01N33/6893 ,  G01N2333/96455 ,  G16B40/00 ,  G16H10/40 ,  G16H50/20 ,  G16H50/30

摘要： Methods and apparatuses for predicting risk of prostate cancer and/or prostate gland volume are provided. More particularly, this disclosure relates to methods and apparatuses for providing the models and employing the models for predicting risk of prostate cancer and/or predicting prostate gland volume. The methods and apparatuses for predicting risk of prostate cancer and/or prostate gland volume are provided using, at least in part, information from a panel of kallikrein markers.

公开(公告)号：US11761962B2

公开(公告)日：2023-09-19

申请号：US14671355

申请日：2015-03-27

申请人： OPKO Diagnostics, LLC

发明人： Vincent Linder ,  David Steinmiller ,  Kim Pettersson ,  Timo Lovgren ,  Hans Lilja ,  Andrew J. Vickers ,  Peter T. Scardino

IPC分类号： G01N33/53 ,  G01N33/574 ,  G16B40/00 ,  G16H50/20 ,  G16B20/00

CPC分类号： G01N33/57434 ,  G16B20/00 ,  G16B40/00 ,  G16H50/20 ,  G01N2333/96455 ,  Y02A90/10

摘要： Aspects of the disclosure relate to improved methods for predicting whether a prostate tissue biopsy obtained from a subject will contain detectable prostate cancer.

公开(公告)号：US20160025732A1

公开(公告)日：2016-01-28

申请号：US14671355

申请日：2015-03-27

申请人： OPKO Diagnostics, LLC

发明人： Vincent Linder ,  David Steinmiller ,  Kim Pettersson ,  Timo Lovgren ,  Hans Lilja ,  Andrew J. Vickers ,  Peter T. Scardino

IPC分类号： G01N33/574 ,  G06F19/24

CPC分类号： G01N33/57434 ,  G01N2333/96455 ,  G16B20/00 ,  G16B40/00 ,  G16H50/20 ,  Y02A90/26

摘要： Aspects of the disclosure relate to improved methods for predicting whether a prostate tissue biopsy obtained from a subject will contain detectable prostate cancer.

摘要翻译： 本公开的方面涉及用于预测从受试者获得的前列腺组织活检是否包含可检测的前列腺癌的改进方法。

公开(公告)号：US20220399121A1

公开(公告)日：2022-12-15

申请号：US17734211

申请日：2022-05-02

申请人： OPKO Diagnostics, LLC

发明人： Yan Dong ,  Andrew J. Vickers ,  Daniel Sjoberg ,  Peter T. Scardino ,  Hans Lilja

IPC分类号： G16H50/30 ,  G01N33/574 ,  G16H10/40 ,  G16H50/20

摘要： Aspects of the disclosure relate to improved methods and systems for active surveillance of subject having non-aggressive prostate cancer.

公开(公告)号：US20230393137A1

公开(公告)日：2023-12-07

申请号：US18325984

申请日：2023-05-30

申请人： OPKO Diagnostics, LLC

发明人： Vincent Linder ,  David Steinmiller ,  Kim Pettersson ,  Timo Lovgren ,  Hans Lilja ,  Andrew J. Vickers ,  Peter T. Scardino

IPC分类号： G01N33/574 ,  G16B40/00 ,  G16H50/20 ,  G16B20/00

CPC分类号： G01N33/57434 ,  G16B40/00 ,  G16H50/20 ,  G16B20/00 ,  Y02A90/10 ,  G01N2333/96455

摘要： Aspects of the disclosure relate to improved methods for predicting whether a prostate tissue biopsy obtained from a subject will contain detectable prostate cancer.

公开(公告)号：US20130273643A1

公开(公告)日：2013-10-17

申请号：US13785058

申请日：2013-03-05

申请人： Arctic Partners Oy ,  OPKO Diagnostics, LLC

发明人： Andrew J. Vickers ,  Peter T. Scardino ,  Hans Lija ,  Vincent Linder ,  David Steinmiller

IPC分类号： G06F19/00 ,  G01N33/68

CPC分类号： G06F19/18 ,  B01L3/502 ,  B01L3/502715 ,  B01L3/502761 ,  B01L2300/0654 ,  B01L2300/0816 ,  B01L2300/087 ,  B01L2400/0487 ,  C12Q1/6886 ,  C12Q2600/112 ,  C12Q2600/158 ,  C12Q2600/16 ,  G01N33/54366 ,  G01N33/57434 ,  G01N33/6893 ,  G01N2333/96455 ,  G06F19/00 ,  G06F19/24 ,  G16H10/40 ,  G16H50/20 ,  G16H50/30

摘要： Methods and apparatuses for predicting risk of prostate cancer and/or prostate gland volume are provided. More particularly, this disclosure relates to methods and apparatuses for providing the models and employing the models for predicting risk of prostate cancer and/or predicting prostate gland volume. The methods and apparatuses for predicting risk of prostate cancer and/or prostate gland volume are provided using, at least in part, information from a panel of kallikrein markers.

摘要翻译： 提供了用于预测前列腺癌和/或前列腺体积的风险的方法和装置。 更具体地，本公开涉及用于提供模型并使用用于预测前列腺癌的风险和/或预测前列腺体积的模型的方法和装置。 用于预测前列腺癌和/或前列腺体积的风险的方法和装置使用至少部分来自激肽释放酶标记物组的信息来提供。