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公开(公告)号：US11033696B2
公开(公告)日：2021-06-15
申请号：US16093174
申请日：2018-10-12
申请人： OptiNose AS
发明人： Per Gisle Djupesland , Michael Leclerc , Ramy A Mahmoud , Shane Siwinski , Joseph Gordon , Justin Fisk
摘要： A nasal delivery device for and method of delivering substance to a nasal airway of a subject, the delivery device comprising: a nosepiece (117) for fitting to a nasal cavity of a subject; a mouthpiece (119) into which the subject in use exhales; a delivery unit, which comprises an actuation part which is manually displaceable to actuate the delivery unit to deliver substance from the nosepiece; and a valve assembly (127) which is fluidly connected to the nosepiece and the mouthpiece, wherein the valve assembly comprises a body element (128) and a valve element (131) which is movably disposed to the body element between closed and open configurations by manual displacement of the actuation part of the delivery unit to provide for an air flow through the nosepiece simultaneously with delivery of substance.
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公开(公告)号：US20190290863A1
公开(公告)日：2019-09-26
申请号：US16093174
申请日：2018-10-12
申请人： OptiNose AS
发明人： Per Gisle Djupesland , Michael Leclerc , Ramy A. Mahmoud , Shane Siwinski , Joseph Gordon , Justin Fisk
摘要： A nasal delivery device for and method of delivering substance to a nasal airway of a subject, the delivery device comprising: a nosepiece (117) for fitting to a nasal cavity of a subject; a mouthpiece (119) into which the subject in use exhales; a delivery unit, which comprises an actuation part which is manually displaceable to actuate the delivery unit to deliver substance from the nosepiece; and a valve assembly (127) which is fluidly connected to the nosepiece and the mouthpiece, wherein the valve assembly comprises a body element (128) and a valve element (131) which is movably disposed to the body element between closed and open configurations by manual displacement of the actuation part of the delivery unit to provide for an air flow through the nosepiece simultaneously with delivery of substance.
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公开(公告)号：US20190083722A1
公开(公告)日：2019-03-21
申请号：US16102898
申请日：2018-08-14
申请人： OptiNose AS
摘要： A nasal delivery device for delivering substance to a nasal cavity of a subject comprises: a housing (15); a nosepiece (17) for fitting to a nasal cavity of the subject; a mouthpiece (19) through which the subject in use exhales; and a flexible coupling (20) which couples the mouthpiece to the housing, wherein the flexible coupling provides for asymmetric translation of the mouthpiece relative to the nosepiece.
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公开(公告)号：US10076614B2
公开(公告)日：2018-09-18
申请号：US14380801
申请日：2013-02-25
申请人： OPTINOSE AS
CPC分类号： A61M15/08 , A61M15/0021 , A61M15/0098 , A61M2202/064 , A61M2205/0216 , A61M2210/0618 , A61M2210/0625
摘要： A nasal delivery device for delivering substance to a nasal cavity of a subject comprises: a housing (15); a nosepiece (17) for fitting to a nasal cavity of the subject; a mouthpiece (19) through which the subject in use exhales; and a flexible coupling (20) which couples the mouthpiece to the housing, wherein the flexible coupling provides for asymmetric translation of the mouthpiece relative to the nosepiece.
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公开(公告)号：US20150013670A1
公开(公告)日：2015-01-15
申请号：US14380827
申请日：2013-02-25
申请人： OPTINOSE AS
发明人： Per Gisle Djupesland , Michael Leclerc , Rany A. Mahmoud , Shane Siwinski , Joseph Gordon , Justin Fisk
CPC分类号： A61M15/08 , A61M15/0018 , A61M15/002 , A61M15/0021 , A61M15/009 , A61M15/0098 , A61M2210/0618
摘要： A nasal delivery device for and method of delivering substance to a nasal airway of a subject, the delivery device comprising: a nosepiece (117) for fitting to a nasal cavity of a subject; a mouthpiece (119) into which the subject in use exhales; a delivery unit, which comprises an actuation part which is manually displaceable to actuate the delivery unit to deliver substance from the nosepiece; and a valve assembly (127) which is fluidly connected to the nosepiece and the mouthpiece, wherein the valve assembly comprises a body element (128) and a valve element (131) which is movably disposed to the body element between closed and open configurations by manual displacement of the actuation part of the delivery unit to provide for an air flow through the nosepiece simultaneously with delivery of substance.
摘要翻译： 一种用于将物质输送到受试者的鼻气道的鼻输送装置和方法，所述输送装置包括：鼻梁（117），用于装配到受试者的鼻腔; 使用者呼气的受试者（119）; 输送单元，其包括可手动地移动以致动输送单元以从物镜输送物质的致动部分; 以及阀组件（127），其流体地连接到所述喷嘴和所述接口管，其中所述阀组件包括主体元件（128）和阀元件（131），所述主体元件（128）和阀元件（131）通过 输送单元的致动部分的手动位移以提供与物质输送同时通过喷嘴的气流。
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公开(公告)号：US10300229B2
公开(公告)日：2019-05-28
申请号：US14380827
申请日：2013-02-25
申请人： OPTINOSE AS
发明人： Per Gisle Djupesland , Michael Leclerc , Ramy A. Mahmoud , Shane Siwinski , Joseph Gordon , Justin Fisk
摘要： A nasal delivery device for and method of delivering substance to a nasal airway of a subject, the delivery device comprising: a nosepiece (117) for fitting to a nasal cavity of a subject; a mouthpiece (119) into which the subject in use exhales; a delivery unit, which comprises an actuation part which is manually displaceable to actuate the delivery unit to deliver substance from the nosepiece; and a valve assembly (127) which is fluidly connected to the nosepiece and the mouthpiece, wherein the valve assembly comprises a body element (128) and a valve element (131) which is movably disposed to the body element between closed and open configurations by manual displacement of the actuation part of the delivery unit to provide for an air flow through the nosepiece simultaneously with delivery of substance.
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公开(公告)号：US20150246194A1
公开(公告)日：2015-09-03
申请号：US14380836
申请日：2013-02-25
申请人： OPTINOSE AS
发明人： Gisle Per Djupesland , Kate Dudgeon , Joseph Gordon , Mark Guarraia , Michael Leclerc , Ramy A. Mahmoud
CPC分类号： A61M15/08 , A61M15/0021 , A61M2202/04 , A61M2202/064 , A61M2205/586 , A61M2210/0618 , A61M2210/0625
摘要： A nasal delivery device comprising: a housing (15); a nosepiece (17) for fitting to a nasal cavity of a subject; a mouthpiece (19) through which the subject in use exhales; and a substance supply unit (21) including an actuation member (23) which extends from one end of the housing and is manually actuated to deliver substance to the nasal cavity of the subject; wherein the housing includes a grip section (27) which is disposed at the one end of the housing from which the actuation member extends, said grip section comprising a first, distal part (28) including at least one projecting grip element (29) by which the subject grips the housing in actuating the actuation member, and a second, proximal part (31) providing a recess (33) in which fingers of the subject are located, said recess promoting proper orientation of the delivery device in a hand of the subject.
摘要翻译： 一种鼻输送装置，包括：壳体（15）; 用于装配到受试者的鼻腔的鼻梁（17）; 用于呼气的受试者的喉舌（19）; 以及物质供应单元（21），其包括致动构件（23），所述致动构件从所述壳体的一端延伸并且被手动地致动以将物质输送到所述对象的鼻腔; 其特征在于，所述壳体包括设置在所述壳体的所述一端延伸的夹持部分（27），所述握持部分包括第一远端部分（28），所述远端部分包括至少一个突出的抓握元件（29） 主体在致动致动构件时握住壳体;以及第二近侧部分（31），其提供被检体的指状物位于其中的凹部（33），所述凹部促进输送装置在手中的适当取向 学科。
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公开(公告)号：US10179216B2
公开(公告)日：2019-01-15
申请号：US14380836
申请日：2013-02-25
申请人： OPTINOSE AS
发明人： Per Gisle Djupesland , Kate Dudgeon , Joseph Gordon , Mark Guarraia , Michael Leclerc , Ramy A Mahmoud
摘要： A nasal delivery device comprising: a housing (15); a nosepiece (17) for fitting to a nasal cavity of a subject; a mouthpiece (19) through which the subject in use exhales; and a substance supply unit (21) including an actuation member (23) which extends from one end of the housing and is manually actuated to deliver substance to the nasal cavity of the subject; wherein the housing includes a grip section (27) which is disposed at the one end of the housing from which the actuation member extends, said grip section comprising a first, distal part (28) including at least one projecting grip element (29) by which the subject grips the housing in actuating the actuation member, and a second, proximal part (31) providing a recess (33) in which fingers of the subject are located, said recess promoting proper orientation of the delivery device in a hand of the subject.
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