公开(公告)号：US20160047749A1

公开(公告)日：2016-02-18

申请号：US14824764

申请日：2015-08-12

Applicant: OPTOLANE TECHNOLOGIES INC.

Inventor： Do Young LEE ,  In Gyun Jeon

IPC: G01N21/64 ,  H01L31/18 ,  H01L31/12

CPC classification number: G01N21/6428 ,  G01N21/6454 ,  G01N2201/062 ,  H01L31/125 ,  H01L31/18

Abstract: The present disclosure a biochip including a side emitting-type light-emitting device, in which the bio-chip includes: a light-emitting device for emitting light from a fluorescent material; reflective layers provided over and under the light-emitting device so as to emit light from the sides of the light-emitting device; and reaction regions formed by etching of flanking regions of the light-emitting device. In the biochip, light emitted from the sides of the light-emitting device causes a biochemical reaction in the reaction regions. According to the present disclosure, light emitted from the light-emitting device moves only laterally without being transferred to the top or bottom of the bio-layer, and is transferred to the reaction regions formed by etching of flanking regions of the light-emitting device, so that a biochemical reaction in the reaction regions can be more efficiently performed.

Abstract translation: 本发明公开了一种生物芯片，其包括侧面发射型发光器件，其中所述生物芯片包括：用于从荧光材料发射光的发光器件; 设置在发光装置的上下的反射层，以从发光装置的侧面发光; 以及通过蚀刻发光器件的侧面区域形成的反应区域。 在生物芯片中，从发光装置的侧面发射的光在反应区域引起生化反应。 根据本公开，从发光装置发射的光仅在横向移动而不转移到生物层的顶部或底部，并且被转移到通过蚀刻发光装置的侧面区域形成的反应区域 ，从而可以更有效地进行反应区域的生化反应。

公开(公告)号：US20180284024A1

公开(公告)日：2018-10-04

申请号：US16001056

申请日：2018-06-06

Applicant: OPTOLANE TECHNOLOGIES INC.

Inventor： Do Young LEE ,  In Gyun JEON

IPC: G01N21/64 ,  H01L31/18 ,  H01L31/12

Abstract: The present disclosure a biochip including a side emitting-type light-emitting device, in which the bio-chip includes: a light-emitting device for emitting light from a fluorescent material; reflective layers provided over and under the light-emitting device so as to emit light from the sides of the light-emitting device; and reaction regions formed by etching of flanking regions of the light-emitting device. In the biochip, light emitted from the sides of the light-emitting device causes a biochemical reaction in the reaction regions. According to the present disclosure, light emitted from the light-emitting device moves only laterally without being transferred to the top or bottom of the bio-layer, and is transferred to the reaction regions formed by etching of flanking regions of the light-emitting device, so that a biochemical reaction in the reaction regions can be more efficiently performed.

公开(公告)号：US20180136127A1

公开(公告)日：2018-05-17

申请号：US15855013

申请日：2017-12-27

Applicant: OPTOLANE TECHNOLOGIES INC.

Inventor： Do Young LEE

IPC: G01N21/64 ,  H01L27/146 ,  H01L27/14 ,  G01N33/53 ,  B01L3/00

Abstract: Provided is a biochip having improved fluorescent signal sensing properties. A filter layer is provided between a bio-layer and a light sensor layer so as to remove noise generated by stray light during a bio-reaction process. Thereby, the sensitivity of the light sensor layer can be enhanced.

公开(公告)号：US20190329254A1

公开(公告)日：2019-10-31

申请号：US16390380

申请日：2019-04-22

Applicant: OPTOLANE Technologies Inc.

Inventor： Sergiy OLEKSANDROV ,  Do Young LEE ,  Min Sik SONG ,  Kyung Hak CHOI

IPC: B01L3/00 ,  C12Q1/6806 ,  C12Q1/686

Abstract: A cartridge for digital real-time Polymerase chain reaction (PCR) includes a microfluidic chamber, a well array, a CMOS photo sensor array and a PCB. The microfluidic chamber includes an inlet formed for injection of a liquid sample, the microfluidic chamber being capable of injection molding. The well array includes a plurality of microwells through which upper and lower portions are perforated and being attached to a lower surface of the microfluidic chamber. The CMOS photo sensor array is disposed below the well array to capture a response image of a sample filled in microwells of the well array. The PCB has a vent formed for vacuum processing of micro flow path formed in the microfluidic chamber, a space formed between the well array and the microfluidic chamber, and a microwell formed in the well array as the liquid sample is injected through the inlet.