公开(公告)号：US20160271611A1

公开(公告)日：2016-09-22

申请号：US15064816

申请日：2016-03-09

Applicant: OPTOLANE Technologies Inc.

Inventor： DoYoung LEE ,  In Gyun JEON ,  An Shik CHOI ,  Kyung Hak CHOI

IPC: B01L7/00 ,  C12Q1/68

CPC classification number: B01L7/52 ,  B01L3/50851 ,  B01L2200/028 ,  B01L2200/147 ,  B01L2300/0663 ,  B01L2300/0681 ,  B01L2300/0819 ,  B01L2300/18 ,  B01L2300/1805 ,  B01L2300/1822 ,  B01L2300/1844 ,  B01L2300/185 ,  C12Q1/686 ,  G01N21/64

Abstract: A polymerase chain reaction (PCR) module is detachably combined with a reader system. The reader system includes a central processing unit (CPU) receiving a photo sensing signal to calculate gene amplification amount in real time and generating a temperature control signal based on a temperature signal and a temperature control information. The PCR module includes a photo sensor assembly, a partition wall, and an interface module. The photo sensor assembly includes a plurality of photo sensors and a temperature sensor. The photo sensors are arranged in an array shape to sense emission light generated from a specimen to generate the photo sensing signal. The partition wall is protruded from the photo sensor assembly to define a reaction space in which the specimen is received. The interface module is electrically connected to the photo sensor assembly to transmit the photo sensing signal and the temperature signal to the reader system.

Abstract translation: 聚合酶链反应（PCR）模块可与读取器系统可拆卸地组合。 读取器系统包括中央处理单元（CPU），其接收感光信号以实时计算基因放大量，并且基于温度信号和温度控制信息产生温度控制信号。 PCR模块包括光传感器组件，分隔壁和接口模块。 光传感器组件包括多个光传感器和温度传感器。 光传感器被布置成阵列形状以检测从样本产生的发射光以产生光感测信号。 分隔壁从光传感器组件突出以限定其中接收样品的反应空间。 接口模块电连接到光传感器组件，以将感光信号和温度信号传输到读取器系统。

公开(公告)号：US20190217303A1

公开(公告)日：2019-07-18

申请号：US16361594

申请日：2019-03-22

Applicant: OPTOLANE Technologies Inc.

Inventor： DoYoung LEE ,  In Gyun JEON ,  An Shik CHOI ,  Kyung Hak CHOI

IPC: B01L7/00 ,  B01L3/00 ,  G01N21/64 ,  C12Q1/686

Abstract: A polymerase chain reaction (PCR) module is detachably combined with a reader system. The reader system includes a central processing unit (CPU) receiving a photo sensing signal to calculate gene amplification amount in real time and generating a temperature control signal based on a temperature signal and a temperature control information. The PCR module includes a photo sensor assembly, a partition wall, and an interface module. The photo sensor assembly includes a plurality of photo sensors and a temperature sensor. The photo sensors are arranged in an array shape to sense emission light generated from a specimen to generate the photo sensing signal. The partition wall is protruded from the photo sensor assembly to define a reaction space in which the specimen is received. The interface module is electrically connected to the photo sensor assembly to transmit the photo sensing signal and the temperature signal to the reader system.

公开(公告)号：US20180284024A1

公开(公告)日：2018-10-04

申请号：US16001056

申请日：2018-06-06

Applicant: OPTOLANE TECHNOLOGIES INC.

Inventor： Do Young LEE ,  In Gyun JEON

IPC: G01N21/64 ,  H01L31/18 ,  H01L31/12

Abstract: The present disclosure a biochip including a side emitting-type light-emitting device, in which the bio-chip includes: a light-emitting device for emitting light from a fluorescent material; reflective layers provided over and under the light-emitting device so as to emit light from the sides of the light-emitting device; and reaction regions formed by etching of flanking regions of the light-emitting device. In the biochip, light emitted from the sides of the light-emitting device causes a biochemical reaction in the reaction regions. According to the present disclosure, light emitted from the light-emitting device moves only laterally without being transferred to the top or bottom of the bio-layer, and is transferred to the reaction regions formed by etching of flanking regions of the light-emitting device, so that a biochemical reaction in the reaction regions can be more efficiently performed.