公开(公告)号：US20190201579A1

公开(公告)日：2019-07-04

申请号：US16312180

申请日：2017-06-19

Applicant: ORGAN TECHNOLOGIES, INC. ,  RIKEN

Inventor： Takashi TSUJI ,  Koh-ei TOYOSHIMA ,  Miho OGAWA

IPC: A61L27/36 ,  A61L27/24 ,  A61L27/60 ,  C12N5/071 ,  C12N5/077

CPC classification number: A61L27/362 ,  A61L27/24 ,  A61L27/36 ,  A61L27/60 ,  C12N5/0627 ,  C12N5/0629 ,  C12N5/0633 ,  C12N5/0656

Abstract: The object of the present invention is to provide an artificial skin having hair follicles, sebaceous glands, and hair pores. The present invention provides a method for manufacturing artificial skin having hair follicles, sebaceous glands, and hair pores, characterized in that it comprises each of the following steps: (A): a step of preparing an artificial skin having dermal and epidermal layers or an artificial skin having only a dermal layer; and (B): a step of transplanting isolated hair follicles to the artificial skin prepared in step (A); wherein said isolated hair follicle comprises a sebaceous gland, and said isolated hair follicle is transplanted to said artificial skin so that the surface of said dermal Layer of said artificial skin is in alignment with the position of the hair pore portion of said isolated hair follicle.