公开(公告)号：US20150351380A1

公开(公告)日：2015-12-10

申请号：US14416148

申请日：2013-07-03

Applicant: OSAKA UNIVERSITY

Inventor： Ryuhei Hayashi ,  Kohji Nishida ,  Ryosuke Katori

IPC: A01N1/02

CPC classification number: A01N1/0226

Abstract: The present invention provides a tissue preservation solution that has good quality for preservation of tissues, organs and cells, and is useful in the fields of regenerative medicine, transplantation medicine, etc. The tissue preservation solution of the present invention comprises a compound having a Nrf2 activating effect. Preferable compounds having a Nrf2 activating effect are electrophiles, and in particular, ebselen and tert-butylhydroquinone. A preferable basal solution of the tissue preservation solution is Hank's balanced salt solution.

Abstract translation: 本发明提供一种保存组织，器官和细胞的良好质量的组织保存液，可用于再生医学，移植药物等领域。本发明的组织保存液含有具有Nrf2 激活效果。 具有Nrf2活化作用的优选化合物是亲电子试剂，尤其是依普硒和叔丁基氢醌。 组织保存液的优选基础溶液是汉克平衡盐溶液。