公开(公告)号：US20190275091A1

公开(公告)日：2019-09-12

申请号：US16346576

申请日：2017-11-01

Applicant: OSAKA UNIVERSITY ,  GENOMIDEA INC.

Inventor： Yasufumi KANEDA ,  Kazuma SAKURA ,  Tomoyuki NISHIKAWA ,  Masanori FUKUSHIMA ,  Toshihiro NAKAJIMA

IPC: A61K35/76 ,  A61P35/00 ,  C12N7/00 ,  A61K39/395

Abstract: The present invention provides an anticancer agent containing the following (1) and (2): (1) HVJ-E (hemagglutinating virus of Japan envelope), (2) an inhibitor of an immune checkpoint protein.

公开(公告)号：US20220202846A1

公开(公告)日：2022-06-30

申请号：US17310002

申请日：2020-01-09

Applicant: OSAKA UNIVERSITY ,  DAICEL CORPORATION

Inventor： Tomoyuki NISHIKAWA ,  Yasufumi KANEDA ,  Kunihiko YAMASHITA ,  Ayano SUZUKI ,  Kazuhiro TERAI

IPC: A61K31/713 ,  C12N15/117 ,  A61P35/00

Abstract: An object of the present disclosure is at least to provide a technique for stimulating immunity in mammals, and the object is fulfilled by double-stranded RNA composed of: RNA composed of a base sequence represented by a sequence A below; and RNA composed of a base sequence represented by a sequence B below, each base of an (N)13-25 portion in the base sequence represented by the sequence A and the base sequence represented by the sequence B being or not being complementary bases, and all of the bases of (N)5-10 portions in the base sequence represented by the sequence A and the base sequence represented by the sequence B being complementary bases, and a Tm value of the (N)5-10 portion being 20° C. or higher: Sequence A: 5′-UUGUCAUAUGGACAAGUCCAAGACU(N)13-25(N)5-10-3′ (SEQ ID No: 1), and Sequence B: 5′-(N)5-10(N)13-25AGUCUUGGACUUGUCCAUAUGACAA-3′ (SEQ ID No: 2).

公开(公告)号：US20230233705A1

公开(公告)日：2023-07-27

申请号：US17925099

申请日：2021-05-14

Applicant: OSAKA UNIVERSITY

Inventor： Hiroki KATO ,  Koichi FUKASE ,  Kazuya KABAYAMA ,  Atsushi SHIMOYAMA ,  Yuichiro KADONAGA ,  Atsushi TOYOSHIMA ,  Atsushi SHINOHARA ,  Yasufumi KANEDA ,  Tomoyuki NISHIKAWA

IPC: A61K47/69 ,  A61P35/00 ,  A61P25/00 ,  A61K41/00 ,  A61P1/18

CPC classification number: A61K47/6923 ,  A61K47/6935 ,  A61P35/00 ,  A61P25/00 ,  A61K41/0038 ,  A61P1/18

Abstract: The present invention relates to a gold nanoparticle-containing medicine, and a treatment of a proliferative disease using the medicine. The present invention also relates to a gold nanoparticle-containing medicine that is bound to an alpha radioactive nucleus, and a treatment of a proliferative disease using the medicine.