公开(公告)号：US20190284228A1

公开(公告)日：2019-09-19

申请号：US16347337

申请日：2017-11-08

Applicant: OSAKA UNIVERSITY ,  KNC LABORATORIES CO., LTD.

Inventor： Haruo SUGIYAMA ,  Fumihiro FUJIKI ,  Masahiro NEYA ,  Shinya KOHNO

IPC: C07J63/00 ,  C12N5/0783 ,  A61P35/00 ,  A61K31/215 ,  A61K31/216 ,  A61K31/40 ,  A61K31/445 ,  A61K31/27 ,  A61K31/265 ,  A61K31/16 ,  A61K31/166 ,  A61K31/196 ,  A61K31/5375

Abstract: Provided are: a compound represented by formula (I); a retinoid metabolic pathway inhibitor comprising the same; an agent for increasing the ratio of memory T cells; a prophylactic and/or therapeutic agent for cancer or an infectious disease; a cancer immunotherapeutic adjuvant; an immunopotentiator; and a method for preparing a T cell population wherein the ratio of memory T cells is increased, said method comprising using the compound of formula (I).