公开(公告)号：US10899790B2

公开(公告)日：2021-01-26

申请号：US16347337

申请日：2017-11-08

Applicant: OSAKA UNIVERSITY ,  KNC LABORATORIES CO., LTD.

Inventor： Haruo Sugiyama ,  Fumihiro Fujiki ,  Masahiro Neya ,  Shinya Kohno

IPC: C07J63/00 ,  A61P35/00 ,  A61K31/16 ,  A61K31/166 ,  A61K31/196 ,  A61K31/215 ,  A61K31/216 ,  A61K31/265 ,  A61K31/27 ,  A61K31/40 ,  A61K31/445 ,  A61K31/5375 ,  C12N5/0783 ,  A61K31/19 ,  A61P37/04 ,  A61P31/00 ,  A61K31/44

Abstract: Provided are: a compound represented by formula (I); a retinoid metabolic pathway inhibitor comprising the same; an agent for increasing the ratio of memory T cells; a prophylactic and/or therapeutic agent for cancer or an infectious disease; a cancer immunotherapeutic adjuvant; an immunopotentiator; and a method for preparing a T cell population wherein the ratio of memory T cells is increased, said method comprising using the compound of formula (I).