公开(公告)号：US20160058528A1

公开(公告)日：2016-03-03

申请号：US14786407

申请日：2014-04-23

Applicant: OSSTEMIMPLANT CO., LTD.

Inventor： Su Kyoung KIM ,  Il Seok JANG ,  Ju Dong SONG ,  Tae Gwan EOM ,  Kyoo Ok CHOI

IPC: A61C8/00

CPC classification number: A61C8/0015 ,  A61C8/0013 ,  A61L27/06 ,  A61L27/14 ,  A61L27/28 ,  A61L2430/12

Abstract: A bioactive-type of hydrophilic dental implant which is made of titanium or titanium alloy having a rough surface, wherein a coating layer of a mixed solution comprising i) an organic pH buffering agent and/or inorganic pH buffering agent and ii) an organic amphiphilic having sulfonic group is formed on the rough surface which was pre-treated to remove a contaminant. The present invention has effects preventing that the dental implant is exposed to air before it is inserted into the alveolar bone and the implant surface is re-contaminated; improving the biocompatibility of the implant, fluid- and blood-affinity, and the initial osseointegration performance; and shortening the osseointegration period, and the surface of the dental implant can be maintained as being hydrophilic for at least 3 years by using a mixed solution of pH buffering agent and organic amphiphilic substance having sulfonic group as a surface coating solution.

Abstract translation: 一种具有粗糙表面的由钛或钛合金制成的生物活性型亲水牙植入体，其中混合溶液的涂层包括i）有机pH缓冲剂和/或无机pH缓冲剂，和ii）有机两亲性 在被预处理以除去污染物的粗糙表面上形成具有磺酸基的化合物。 本发明具有防止牙齿植入物在其插入牙槽骨内而暴露于空气并且植入物表面被再污染的作用; 改善植入物的生物相容性，流体和血液亲和力以及初始骨整合性能; 并缩短骨整合时间，并且通过使用pH缓冲剂和具有磺酸基的有机两亲物质作为表面包衣溶液的混合溶液，可将牙科植入物的表面保持至少3年的亲水性。

公开(公告)号：US20200297586A1

公开(公告)日：2020-09-24

申请号：US16651619

申请日：2018-09-28

Applicant: OSSTEMIMPLANT CO., LTD.

Inventor： Il Seok JANG ,  Hanna PARK ,  Su Kyoung KIM ,  Ju Dong SONG ,  Tae Gwan EOM

IPC: A61K6/887 ,  A61K6/20

Abstract: A fluorine coating agent having enhanced dental tubule permeability and coating endurance, and a method for preparing the same. The fluorine coating agent applied on the surface of a tooth is enhanced in abrasion resistance to increase a period of time during which a coating membrane lasts, thereby preventing dental caries. Further, the curing time of the fluorine coating agent can be controlled to allow the agent to permeate and thus block the dental tubule.