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    DENTAL IMPLANT COATED WITH A MIXED SOLUTION OF CHEMICAL BUFFERING AGENT AND ORGANIC AMPHIPHILIC SUBSTANCE AND A PREPARATION PROCESS THEREOF
    1.
    发明申请
    DENTAL IMPLANT COATED WITH A MIXED SOLUTION OF CHEMICAL BUFFERING AGENT AND ORGANIC AMPHIPHILIC SUBSTANCE AND A PREPARATION PROCESS THEREOF 有权
    用化学缓冲剂和有机活性物质的混合溶液涂覆的牙科植入物及其制备方法

    公开(公告)号：US20160058528A1

    公开(公告)日：2016-03-03

    申请号：US14786407

    申请日：2014-04-23

    Applicant: OSSTEMIMPLANT CO., LTD.

    Inventor： Su Kyoung KIM ,  Il Seok JANG ,  Ju Dong SONG ,  Tae Gwan EOM ,  Kyoo Ok CHOI

    IPC: A61C8/00

    CPC classification number: A61C8/0015 ,  A61C8/0013 ,  A61L27/06 ,  A61L27/14 ,  A61L27/28 ,  A61L2430/12

    Abstract: A bioactive-type of hydrophilic dental implant which is made of titanium or titanium alloy having a rough surface, wherein a coating layer of a mixed solution comprising i) an organic pH buffering agent and/or inorganic pH buffering agent and ii) an organic amphiphilic having sulfonic group is formed on the rough surface which was pre-treated to remove a contaminant. The present invention has effects preventing that the dental implant is exposed to air before it is inserted into the alveolar bone and the implant surface is re-contaminated; improving the biocompatibility of the implant, fluid- and blood-affinity, and the initial osseointegration performance; and shortening the osseointegration period, and the surface of the dental implant can be maintained as being hydrophilic for at least 3 years by using a mixed solution of pH buffering agent and organic amphiphilic substance having sulfonic group as a surface coating solution.

    Abstract translation: 一种具有粗糙表面的由钛或钛合金制成的生物活性型亲水牙植入体，其中混合溶液的涂层包括i）有机pH缓冲剂和/或无机pH缓冲剂，和ii）有机两亲性 在被预处理以除去污染物的粗糙表面上形成具有磺酸基的化合物。 本发明具有防止牙齿植入物在其插入牙槽骨内而暴露于空气并且植入物表面被再污染的作用; 改善植入物的生物相容性，流体和血液亲和力以及初始骨整合性能; 并缩短骨整合时间，并且通过使用pH缓冲剂和具有磺酸基的有机两亲物质作为表面包衣溶液的混合溶液，可将牙科植入物的表面保持至少3年的亲水性。

    IMPLANT COATING MATERIAL FOR ENHANCING A BIOACTIVITY AND OSSEOINTEGRATION OF IMPLANT SURFACE, AND THE METHOD FOR MANUFACTURING AND STORING THE SAME
    5.
    发明申请
    IMPLANT COATING MATERIAL FOR ENHANCING A BIOACTIVITY AND OSSEOINTEGRATION OF IMPLANT SURFACE, AND THE METHOD FOR MANUFACTURING AND STORING THE SAME 审中-公开
    用于增强植入表面的生物活性和操作的植入物涂料及其制造和存储方法

    公开(公告)号：US20160143709A1

    公开(公告)日：2016-05-26

    申请号：US14903653

    申请日：2013-10-25

    Applicant: OSSTEMIMPLANT CO., LTD.

    Inventor： II Seok Jang ,  Su Kyoung KIM ,  Ju Dong SONG ,  Tae Gwan EOM ,  Kyoo Ok CHOI

    IPC: A61C8/00 ,  A61L27/54 ,  A61L27/06 ,  A61L27/28

    CPC classification number: A61C8/0037 ,  A61C8/0013 ,  A61C2008/0046 ,  A61L27/06 ,  A61L27/28 ,  A61L27/50 ,  A61L27/54 ,  A61L2300/216 ,  A61L2300/224 ,  A61L2300/428 ,  A61L2400/18 ,  A61L2420/02 ,  A61L2430/12

    Abstract: A method for forming a coating film of a material for enhancing bioactivity, such as a water-soluble vitamin, on a surface of a dental implant, and a dental implant produced by the method, in order to overcome the limitations in improving osseointegration capability, which result from existing physical surface treatments, such as RBM and SLA surface treatments. The methods enable the SLA-pretreated implant surface to have blood affinity and an enhanced bioactive function, thereby providing a method for producing a dental implant which has excellent biocompatibility and high osseointegration capability after the implant procedure and thus has enhanced bioactivity, and a dental implant produced by the method. The surface of the dental implant, from which organic pollutants have been removed, are coated with a bioactive material, thereby enhancing blood affinity and bioactivity of the implant and thus improving initial osseointegration capability of the implant.

    Abstract translation: 为了克服改善骨整合能力的限制，在牙科植入物表面形成用于增强生物活性的材料的涂膜，例如水溶性维生素的涂膜和通过该方法生产的牙科植入物的方法， 这是由现有的物理表面处理产生的，如RBM和SLA表面处理。 这些方法使得SLA预处理的植入物表面具有血液亲和性和增强的生物活性功能，从而提供了一种用于生产牙植入物的方法，所述牙植入物在植入程序之后具有优异的生物相容性和高骨整合能力，因此具有增强的生物活性， 由该方法生产。 已经去除了有机污染物的牙科植入物的表面被生物活性材料包覆，从而增强植入物的血亲和力和生物活性，从而提高植入物的初始骨整合能力。

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