公开(公告)号：US10799696B2

公开(公告)日：2020-10-13

申请号：US15904036

申请日：2018-02-23

Applicant: Oculeve, Inc.

Inventor： James Donald Loudin ,  Amitava Gupta ,  John Wardle ,  Christopher William Stivers ,  Anand Doraiswamy ,  Marie Dvorak Christ ,  F. Richard Christ

IPC: A61N1/05 ,  H01B1/12 ,  A61N1/04 ,  C08F220/54 ,  C08F230/08 ,  C08F220/20 ,  A61N1/36

Abstract: Described herein are polymer formulations for facilitating electrical stimulation of nasal or sinus tissue. The polymer formulations may be hydrogels that are prepared by a UV cross-linking process. The hydrogels may be included as a component of nasal stimulator devices that electrically stimulate the lacrimal gland to improve tear production and treat dry eye. Additionally, devices and methods for manufacturing the nasal stimulators, including shaping of the hydrogel, are described herein.

公开(公告)号：US20210069496A1

公开(公告)日：2021-03-11

申请号：US17018888

申请日：2020-09-11

Applicant: Oculeve, Inc.

Inventor： James Donald Loudin ,  Amitava Gupta ,  John L. Wardle ,  Christopher William Stivers ,  Anand Doraiswamy ,  Marie Dvorak Christ ,  F. Richard Christ

IPC: A61N1/05 ,  H01B1/12 ,  A61N1/04 ,  C08F220/54 ,  C08F230/08 ,  C08F220/20

Abstract: Described herein are polymer formulations for facilitating electrical stimulation of nasal or sinus tissue. The polymer formulations may be hydrogels that are prepared by a UV cross-linking process. The hydrogels may be included as a component of nasal stimulator devices that electrically stimulate the lacrimal gland to improve tear production and treat dry eye. Additionally, devices and methods for manufacturing the nasal stimulators, including shaping of the hydrogel, are described herein.

公开(公告)号：US09770583B2

公开(公告)日：2017-09-26

申请号：US14630471

申请日：2015-02-24

Applicant: Oculeve, Inc.

Inventor： Amitava Gupta ,  Marie Dvorak Christ ,  F. Richard Christ

IPC: A61N1/04 ,  A61N1/05 ,  A61K9/00 ,  C08J3/075 ,  H01B1/12 ,  C08F220/54 ,  C08F230/08 ,  A61N1/36

CPC classification number: A61N1/0546 ,  A61N1/0456 ,  A61N1/0496 ,  A61N1/36014 ,  C08F220/54 ,  C08F230/08 ,  H01B1/125 ,  Y10T29/49826 ,  Y10T29/49885 ,  C08F226/10 ,  C08F220/20 ,  C08F2222/1013 ,  C08F2230/085

Abstract: Described herein are polymer formulations for facilitating electrical stimulation of nasal or sinus tissue. The polymer formulations may be hydrogels that are prepared by a UV cross-linking process. The hydrogels may be included as a component of nasal stimulator devices that electrically stimulate the lacrimal gland to improve tear production and treat dry eye. Additionally, devices and methods for manufacturing the nasal stimulators, including shaping of the hydrogel, are described herein.

公开(公告)号：US09956397B2

公开(公告)日：2018-05-01

申请号：US15700935

申请日：2017-09-11

Applicant: Oculeve, Inc.

Inventor： James Donald Loudin ,  Amitava Gupta ,  Marie Dvorak Christ ,  F. Richard Christ

IPC: A61N1/05 ,  A61N1/04 ,  C08F220/54 ,  H01B1/12 ,  C08F230/08 ,  A61N1/36

CPC classification number: A61N1/0546 ,  A61N1/0456 ,  A61N1/0496 ,  A61N1/36014 ,  C08F220/54 ,  C08F230/08 ,  H01B1/125 ,  Y10T29/49826 ,  Y10T29/49885 ,  C08F226/10 ,  C08F220/20 ,  C08F2222/1013 ,  C08F2230/085

Abstract: Described herein are polymer formulations for facilitating electrical stimulation of nasal or sinus tissue. The polymer formulations may be hydrogels that are prepared by a UV cross-linking process. The hydrogels may be included as a component of nasal stimulator devices that electrically stimulate the lacrimal gland to improve tear production and treat dry eye. Additionally, devices and methods for manufacturing the nasal stimulators, including shaping of the hydrogel, are described herein.