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公开(公告)号：US20230036216A1
公开(公告)日：2023-02-02
申请号：US17961219
申请日：2022-10-06
发明人： Maung Kyaw Khaing Oo , Xudong Fan
摘要： An optofluidic diagnostic system and methods for rapid analyte detections. The system comprises an optofluidic sensor array, a test plate and an optical detection cartridge. The sensor array supports one or more distinct sensor units, each having a reactor section designed to temporarily enter a series of different kinds of wells in the test plate. One kind of well is a sample reservoir that holds reagent solution to be transferred into the reactor section. Another kind of well is a drainage chamber that removes reagent solution from the reactor section. A third kind of well is a colorant reservoir that holds a colorant reagent transferable into a reactor section. Finally, the sensor unit is transferred to the optical detection cartridge where it is placed into an isolation booth during the optical detection process so that its flat observation face is stationed in a viewing window opposite an optical detector lens.
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公开(公告)号：US11860108B2
公开(公告)日：2024-01-02
申请号：US17961219
申请日：2022-10-06
发明人： Maung Kyaw Khaing Oo , Xudong Fan
CPC分类号： G01N21/77 , B01L3/5085 , G01N21/78 , B01L2300/0663 , B01L2300/0809 , B01L2300/0829 , B01L2300/0832 , B01L2300/0851 , B01L2300/0858 , B01L2300/168 , G01N21/76 , G01N2021/757 , G01N2021/7786 , G01N2201/0446
摘要： An optofluidic diagnostic system and methods for rapid analyte detections. The system comprises an optofluidic sensor array, a test plate and an optical detection cartridge. The sensor array supports one or more distinct sensor units, each having a reactor section designed to temporarily enter a series of different kinds of wells in the test plate. One kind of well is a sample reservoir that holds reagent solution to be transferred into the reactor section. Another kind of well is a drainage chamber that removes reagent solution from the reactor section. A third kind of well is a colorant reservoir that holds a colorant reagent transferable into a reactor section. Finally, the sensor unit is transferred to the optical detection cartridge where it is placed into an isolation booth during the optical detection process so that its flat observation face is stationed in a viewing window opposite an optical detector lens.
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公开(公告)号：US20210031201A1
公开(公告)日：2021-02-04
申请号：US17046040
申请日：2019-04-15
发明人： Maung Kyaw Khaing Oo , Xudong Fan
IPC分类号： B01L3/00
摘要： A drainage system and method for diagnostic systems and the like. The system comprises a base with a hinged lid. A plenum chamber is formed either in the base or the lid. When formed in the lid, the plenum chamber is configured to receive a positive pressure from a pneumatic pump. When formed in the base, the plenum chamber is configured to receive a negative pressure from a pneumatic pump. The base has an elevated table, from which an array of posts project. A semipermeable layer is placed on the truncated tips of the posts, and a microfluidic plate is set over the semipermeable layer. The lid is then closed to apply compression against the sandwiched plate and semipermeable layer. The pump is activated to establish a differential pressure through the plenum chamber, however the semipermeable layer provides pneumatic resistance to air flowing through the microfluidic channel(s) in the plate.
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公开(公告)号：US11692941B2
公开(公告)日：2023-07-04
申请号：US17509806
申请日：2021-10-25
发明人： Maung Kyaw Khaing Oo , Xudong Fan
CPC分类号： G01N21/77 , B01L3/5085 , G01N21/78 , B01L2300/0663 , B01L2300/0809 , B01L2300/0829 , B01L2300/0832 , B01L2300/0851 , B01L2300/0858 , B01L2300/168 , G01N21/76 , G01N2021/757 , G01N2021/7786 , G01N2201/0446
摘要： An optofluidic diagnostic system and methods for rapid analyte detections. The system comprises an optofluidic sensor array, a test plate and an optical detection cartridge. The sensor array supports one or more distinct sensor units, each having a reactor section designed to temporarily enter a series of different kinds of wells in the test plate. One kind of well is a sample reservoir that holds reagent solution to be transferred into the reactor section. Another kind of well is a drainage chamber that removes reagent solution from the reactor section. A third kind of well is a colorant reservoir that holds a colorant reagent transferable into a reactor section. Finally, the sensor unit is transferred to the optical detection cartridge where it is placed into an isolation booth during the optical detection process so that its flat observation face is stationed in a viewing window opposite an optical detector lens.
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公开(公告)号：US11181481B2
公开(公告)日：2021-11-23
申请号：US16489420
申请日：2018-03-08
发明人： Maung Kyaw Khaing Oo , Xudong Fan
摘要： An optofluidic diagnostic system and methods for rapid analyte detections. The system comprises an optofluidic sensor array, a test plate and an optical detection cartridge. The sensor array supports one or more distinct sensor units, each having a reactor section designed to temporarily enter a series of different kinds of wells in the test plate. One kind of well is a sample reservoir that holds reagent solution to be transferred into the reactor section. Another kind of well is a drainage chamber that removes reagent solution from the reactor section. A third kind of well is a colorant reservoir that holds a colorant reagent transferable into a reactor section. Finally, the sensor unit is transferred to the optical detection cartridge where it is placed into an isolation booth during the optical detection process so that its flat observation face is stationed in a viewing window opposite an optical detector lens.
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公开(公告)号：US20190383750A1
公开(公告)日：2019-12-19
申请号：US16489420
申请日：2018-03-08
发明人： Maung Kyaw Khaing Oo , Xudong Fan
摘要： An optofluidic diagnostic system and methods for rapid analyte detections. The system comprises an optofluidic sensor array, a test plate and an optical detection cartridge. The sensor array supports one or more distinct sensor units, each having a reactor section designed to temporarily enter a series of different kinds of wells in the test plate. One kind of well is a sample reservoir that holds reagent solution to be transferred into the reactor section. Another kind of well is a drainage chamber that removes reagent solution from the reactor section. A third kind of well is a colorant reservoir that holds a colorant reagent transferable into a reactor section. Finally, the sensor unit is transferred to the optical detection cartridge where it is placed into an isolation booth during the optical detection process so that its flat observation face is stationed in a viewing window opposite an optical detector lens.
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