-
公开(公告)号:US20060263424A1
公开(公告)日:2006-11-23
申请号:US11449041
申请日:2006-06-07
申请人: Otto Damon , Herwig Jennewein , Thomas Lentner , Franz Schwarz , Robert Veigl
发明人: Otto Damon , Herwig Jennewein , Thomas Lentner , Franz Schwarz , Robert Veigl
IPC分类号: A61K31/407 , A61K9/20
CPC分类号: A61K31/42 , A61K9/16 , A61K9/1641 , A61K9/2077 , A61K31/424 , A61K31/43 , A61K2300/00
摘要: A pharmaceutical composition comprising an active ingredient and clavulanate wherein the clavulanate is in the form of granulated and hydrophobised particles; and intermediates in its preparation, e.g. clavulanate in granulated and/or hydrophobised form.
摘要翻译: 一种药物组合物,其包含活性成分和克拉维酸盐,其中所述克拉维酸盐为颗粒化和疏水化颗粒的形式; 和其制备中的中间体,例如 棒状和/或疏水形式的克拉维酸。
-
公开(公告)号:US08652517B2
公开(公告)日:2014-02-18
申请号:US11233121
申请日:2005-09-22
申请人: Reinhard Entner , Herwig Jennewein
发明人: Reinhard Entner , Herwig Jennewein
CPC分类号: A61K9/286 , A61K9/2813 , A61K9/2826
摘要: A process for the coating of tablet cores, said tablet core comprising an effective amount of at least one pharmaceutically active compound, comprising spraying a coating solution or suspension comprising a sugar, or a starch, or a mixture of a sugar and a starch onto the tablets or tablet cores with the proviso that film-forming agents in the coating solution or suspension are excluded, to obtain coated tablets, such coated tablets and corresponding coating mixtures.
摘要翻译: 一种用于包衣片芯的方法,所述片芯包含有效量的至少一种药学活性化合物,包括将包含糖或淀粉或糖和淀粉的混合物的包衣溶液或悬浮液喷雾到 片剂或片剂核心,条件是排除涂层溶液或悬浮液中的成膜剂,以获得包衣片剂,这种包衣片剂和相应的涂料混合物。
-
公开(公告)号:US20090170753A1
公开(公告)日:2009-07-02
申请号:US12374489
申请日:2007-07-24
申请人: Christian Welz , Gottfried Stubauer , Andreas Schmarda , Herwig Jennewein , Ingolf Macher , Johannes Ludescher
发明人: Christian Welz , Gottfried Stubauer , Andreas Schmarda , Herwig Jennewein , Ingolf Macher , Johannes Ludescher
摘要: The present invention relates to pharmaceutical compositions comprising a pharmaceutically acceptable salt of caspofungin as active ingredient being useful for the prevention and/or treatment of fungal infections. Said compositions additionally comprise specific bulking agents and small amounts or no amounts of an additional pH modifier and may be in a liquid or solid form, e.g. may be lyophilized compositions. Said compositions show good stability and reduced amounts of sub-visible particulate matter formed in solutions which are reconstituted from the lyophilized product.
摘要翻译: 本发明涉及包含卡泊芬净的药学上可接受的盐作为活性成分的药物组合物,其可用于预防和/或治疗真菌感染。 所述组合物另外包含特定的填充剂和少量或不含量的另外的pH调节剂,并且可以是液体或固体形式,例如。 可以是冻干组合物。 所述组合物显示良好的稳定性和减少在从冻干产物重构的溶液中形成的亚可见颗粒物质的量。
-
公开(公告)号:US08232245B2
公开(公告)日:2012-07-31
申请号:US12374489
申请日:2007-07-24
申请人: Christian Welz , Gottfried Stubauer , Andreas Schmarda , Herwig Jennewein , Ingolf Macher , Johannes Ludescher
发明人: Christian Welz , Gottfried Stubauer , Andreas Schmarda , Herwig Jennewein , Ingolf Macher , Johannes Ludescher
IPC分类号: A61K38/12
摘要: The present invention relates to pharmaceutical compositions comprising a pharmaceutically acceptable salt of caspofungin as active ingredient being useful for the prevention and/or treatment of fungal infections. The compositions additionally comprise specific bulking agents and small amounts or no amounts of an additional pH modifier and may be in a liquid or solid form, e.g. may be lyophilized compositions. The compositions show good stability and reduced amounts of sub-visible particulate matter formed in solutions which are reconstituted from the lyophilized product.
摘要翻译: 本发明涉及包含卡泊芬净的药学上可接受的盐作为活性成分的药物组合物,其可用于预防和/或治疗真菌感染。 组合物另外包含特定的填充剂和少量或不含量的另外的pH调节剂,并且可以是液体或固体形式,例如, 可以是冻干组合物。 组合物显示良好的稳定性和减少在从冻干产品重构的溶液中形成的亚可见颗粒物质的量。
-
公开(公告)号:US20090176755A1
公开(公告)日:2009-07-09
申请号:US12208417
申请日:2008-09-11
申请人: Herwig Jennewein
发明人: Herwig Jennewein
IPC分类号: A61K31/546
CPC分类号: A61K31/546 , A61K9/0095 , A61K9/1652
摘要: The present invention relates to cefdinir. More particularly to pharmaceutical formulations comprising cefdinir in a defined polymorphic form and processes for the preparation thereof. Furthermore, the present invention relates to processes to keep cefdinir in a defined polymorphic form.
摘要翻译: 本发明涉及头孢地尼。 更具体地涉及包含具有确定的多晶型形式的头孢地尼的药物制剂及其制备方法。 此外,本发明涉及将头孢地尼酮保持在所定义的多态形式中的方法。
-
公开(公告)号:US20130028940A1
公开(公告)日:2013-01-31
申请号:US13531732
申请日:2012-06-25
申请人: Christian Welz , Gottfried Stubauer , Andreas Schmarda , Herwig Jennewein , Ingolf Macher , Johannes Ludescher
发明人: Christian Welz , Gottfried Stubauer , Andreas Schmarda , Herwig Jennewein , Ingolf Macher , Johannes Ludescher
摘要: The present invention relates to pharmaceutical compositions comprising a pharmaceutically acceptable salt of caspofungin as active ingredient being useful for the prevention and/or treatment of fungal infections. Said compositions additionally comprise specific bulking agents and small amounts or no amounts of an additional pH modifier and may be in a liquid or solid form, e.g. may be lyophilized compositions. Said compositions show good stability and reduced amounts of sub-visible particulate matter formed in solutions which are reconstituted from the lyophilized product.
摘要翻译: 本发明涉及包含卡泊芬净的药学上可接受的盐作为活性成分的药物组合物,其可用于预防和/或治疗真菌感染。 所述组合物另外包含特定的填充剂和少量或不含量的另外的pH调节剂,并且可以是液体或固体形式,例如。 可以是冻干组合物。 所述组合物显示良好的稳定性和减少在从冻干产物重构的溶液中形成的亚可见颗粒物质的量。
-
公开(公告)号:US06727243B1
公开(公告)日:2004-04-27
申请号:US09445741
申请日:1999-12-10
IPC分类号: A61K3154
CPC分类号: A61K9/143 , A61K9/146 , A61K9/2009 , A61K9/2018 , A61K9/2027 , A61K9/2054 , A61K31/545
摘要: Cefuroxime axetil in a non-gelatinous form on contact with an aqueous liquid, e.g., in the form of a solid dispersion on a carrier, e.g., useful for the production of pharmaceutical compositions comprising cefuroxime axetil as an active ingredient and use of cefuroxime axetil in the manufacture of an oral dosage form which does not exhibit an adverse food effect.
摘要翻译: 非水凝胶形式的头孢呋辛酯与水性液体接触,例如以载体为固体分散体的形式,例如可用于制备包含头孢呋辛酯作为活性成分的药物组合物,以及头孢呋辛酯的使用 制造不具有不利食物作用的口服剂型。
-
公开(公告)号:US20070128268A1
公开(公告)日:2007-06-07
申请号:US11295929
申请日:2005-12-07
申请人: Herwig Jennewein
发明人: Herwig Jennewein
IPC分类号: A61K31/545 , A61K9/48 , A61K9/20
CPC分类号: A61K31/546 , A61K9/0095 , A61K9/1652
摘要: The present invention relates to cefdinir. More particularly to pharmaceutical formulations comprising cefdinir in a defined polymorphic form and processes for the preparation thereof. Furthermore, the present invention relates to processes to keep cefdinir in a defined polymorphic form.
摘要翻译: 本发明涉及头孢地尼。 更具体地涉及包含具有确定的多晶型形式的头孢地尼的药物制剂及其制备方法。 此外,本发明涉及将头孢地尼酮保持在所定义的多态形式中的方法。
-
公开(公告)号:US20060034917A1
公开(公告)日:2006-02-16
申请号:US11233121
申请日:2005-09-22
申请人: Reinhard Entner , Herwig Jennewein
发明人: Reinhard Entner , Herwig Jennewein
CPC分类号: A61K9/286 , A61K9/2813 , A61K9/2826
摘要: A process for the coating of tablet cores, said tablet core comprising an effective amount of at least one pharmaceutically active compound, comprising spraying a coating solution or suspension comprising a sugar, or a starch, or a mixture of a sugar and a starch onto the tablets or tablet cores with the proviso that film-forming agents in the coating solution or suspension are excluded, to obtain coated tablets, such coated tablets and corresponding coating mixtures.
摘要翻译: 一种用于包衣片芯的方法,所述片芯包含有效量的至少一种药学活性化合物,包括将包含糖或淀粉或糖和淀粉的混合物的包衣溶液或悬浮液喷雾到 片剂或片剂核心,条件是排除涂层溶液或悬浮液中的成膜剂,以获得包衣片剂,这种包衣片剂和相应的涂料混合物。
-
-
-
-
-
-
-
-