专利检索 ap:("PATRICK A DIASSI" OR "PACIFICO A PRINCIPE") AND inv:"DIASSI PATRICK A" 第 1 页

1.

发明授权
Process for preparing acetals and ketals of 2beta,16alpha,17alpha-trihydroxy seroids 失效
标题翻译：制备2BETA，16ALPHA，17ALPHA-TRIHYDROXY SEROIDS的乙酸和乙酯的方法

公开(公告)号：US3600280A

公开(公告)日：1971-08-17

申请号：US3600280D

申请日：1969-06-06

申请人： PATRICK A DIASSI , PACIFICO A PRINCIPE

发明人： DIASSI PATRICK A , PRINCIPE PACIFICO A

IPC分类号： C12P33/00 , C07C167/08

CPC分类号： C12P33/00 , Y10S435/912

摘要： THIS INVENTION RELATES TO THE PRODUCTION OF ACETALS AND KETALS OF 2B,16A-DIHYDROXYHYDROCORTISONE AND ACYL DERIVATIVES THEREOF. THESE COMPOUNDS ARE PREPARED BY SUBJECTING ACETALS AND KETALS OF 16A-HYDROXYCORTEXOLONE TO THE ACTION OF ENZYMES OF ABSIDIA COERULEA. THE FINAL PRODUCTS OF THIS INVENTION ARE THERAPEUTICALLY USEFUL COMPOUNDS POSSESSING ANTI-INFLAMMATORY AND PROGESTATIONAL ACIVITY. IN ADDITION, THE PRODUCTS OF THIS INVENTION ARE USEFUL AS ANTI-OXIDANTS AND ANTI-CORROSIVE AGENTS. THEY ARE ALSO SURFACTANTS AND THUS MAY BE EMPLOYED AS EMULSIFIERS AND WETTING AGENTS.