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公开(公告)号：US09181252B2
公开(公告)日：2015-11-10
申请号：US14621723
申请日：2015-02-13
Applicant: Pfizer Inc.
Inventor： David A. Griffith , Robert L. Dow , Scott W. Bagley , Aaron Smith
IPC: C07D471/20 , C07D519/00
CPC classification number: C07D471/20 , C07D519/00
Abstract: The invention provides a compound of Formula (I) or a pharmaceutically acceptable salt thereof; wherein G is R1, R2 and R3 are as described herein; pharmaceutical compositions thereof; and the use thereof in treating diseases, conditions or disorders modulated by the inhibition of an acetyl-CoA carboxylase enzyme(s) in an animal.
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公开(公告)号：US20140288049A1
公开(公告)日：2014-09-25
申请号：US14299497
申请日：2014-06-09
Applicant: Pfizer Inc.
Inventor： Philip A. Carpino , Edward L. Conn , Robert L. Dow , Matthew S. Dowling , David Hepworth , Daniel Wei-Shung Kung , Suvi Orr , Benjamin N. Rocke , Roger B. Ruggeri , Matthew F. Sammons , Joseph S. Warmus , Yan Zhang
IPC: C07D239/56 , C07D401/04 , C07D405/04 , C07D403/04 , C07D471/04 , A61K31/5377 , C07D417/04 , C07D403/06 , C07D403/10 , C07D401/06 , C07D413/06 , A61K31/513 , C07D409/04
CPC classification number: C07D239/56 , A61K31/352 , A61K31/37 , A61K31/513 , A61K31/5377 , A61K45/06 , C07D401/04 , C07D401/06 , C07D401/10 , C07D403/04 , C07D403/06 , C07D403/10 , C07D403/12 , C07D405/04 , C07D405/06 , C07D405/10 , C07D409/04 , C07D409/10 , C07D413/06 , C07D417/04 , C07D417/10 , C07D471/04 , C07D487/04 , A61K2300/00
Abstract: Myeloperoxidase inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to treat, for example, cardiovascular conditions.
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公开(公告)号：US20150152109A1
公开(公告)日：2015-06-04
申请号：US14621723
申请日：2015-02-13
Applicant: Pfizer Inc.
Inventor： David A. Griffith , Robert L. Dow , Scott W. Bagley , Aaron Smith
IPC: C07D471/20
CPC classification number: C07D471/20 , C07D519/00
Abstract: The invention provides a compound of Formula (I) or a pharmaceutically acceptable salt thereof; wherein G is R1, R2 and R3 are as described herein; pharmaceutical compositions thereof; and the use thereof in treating diseases, conditions or disorders modulated by the inhibition of an acetyl-CoA carboxylase enzyme(s) in an animal.
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公开(公告)号：US20160304469A1
公开(公告)日：2016-10-20
申请号：US15191943
申请日：2016-06-24
Applicant: Pfizer Inc.
Inventor： Philip A. Carpino , Edward L. Conn , Robert L. Dow , Matthew S. Dowling , David Hepworth , Daniel Wei-Shung Kung , Suvi Orr , Benjamin N. Rocke , Roger B. Ruggeri , Matthew F. Sammons , Joseph S. Warmus , Yan Zhang
IPC: C07D239/56 , A61K45/06 , C07D401/04 , C07D405/04 , C07D403/04 , C07D471/04 , C07D409/04 , C07D417/04 , C07D405/10 , C07D405/06 , C07D403/06 , C07D403/10 , C07D401/06 , C07D413/06 , A61K31/5377 , C07D403/12 , A61K31/513
CPC classification number: C07D239/56 , A61K31/352 , A61K31/37 , A61K31/513 , A61K31/5377 , A61K45/06 , C07D401/04 , C07D401/06 , C07D401/10 , C07D403/04 , C07D403/06 , C07D403/10 , C07D403/12 , C07D405/04 , C07D405/06 , C07D405/10 , C07D409/04 , C07D409/10 , C07D413/06 , C07D417/04 , C07D417/10 , C07D471/04 , C07D487/04 , A61K2300/00
Abstract: Myeloperoxidase inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to treat, for example, cardiovascular conditions.
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Patent Agency Ranking
公开(公告)号：US09873673B2
公开(公告)日：2018-01-23
申请号：US15191943
申请日：2016-06-24
Applicant: Pfizer Inc.
Inventor： Philip A. Carpino , Edward L. Conn , Robert L. Dow , Matthew S. Dowling , David Hepworth , Daniel Wei-Shung Kung , Suvi Orr , Benjamin N. Rocke , Roger B. Ruggeri , Matthew F. Sammons , Joseph S. Warmus , Yan Zhang
IPC: C07D239/56 , A61K31/513 , A61K31/352 , A61K31/5377 , A61K45/06 , C07D401/04 , C07D401/06 , C07D401/10 , C07D403/04 , C07D403/06 , C07D403/10 , C07D403/12 , C07D405/04 , C07D405/10 , C07D409/04 , C07D409/10 , C07D413/06 , C07D417/10 , C07D487/04 , C07D417/04 , C07D471/04 , A61K31/37 , C07D405/06
CPC classification number: C07D239/56 , A61K31/352 , A61K31/37 , A61K31/513 , A61K31/5377 , A61K45/06 , C07D401/04 , C07D401/06 , C07D401/10 , C07D403/04 , C07D403/06 , C07D403/10 , C07D403/12 , C07D405/04 , C07D405/06 , C07D405/10 , C07D409/04 , C07D409/10 , C07D413/06 , C07D417/04 , C07D417/10 , C07D471/04 , C07D487/04 , A61K2300/00
Abstract: Myeloperoxidase inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to treat, for example, cardiovascular conditions.
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公开(公告)号：US09399626B2
公开(公告)日：2016-07-26
申请号：US14299497
申请日：2014-06-09
Applicant: Pfizer Inc.
Inventor： Philip A. Carpino , Edward L. Conn , Robert L. Dow , Matthew S. Dowling , David Hepworth , Daniel Wei-Shung Kung , Suvi Orr , Benjamin N. Rocke , Roger B. Ruggeri , Matthew F. Sammons , Joseph S. Warmus , Yan Zhang
IPC: C07D239/56 , A61K31/513 , A61K31/352 , A61K31/5377 , A61K45/06 , C07D401/04 , C07D401/06 , C07D401/10 , C07D403/04 , C07D403/06 , C07D403/10 , C07D403/12 , C07D405/04 , C07D405/10 , C07D409/04 , C07D409/10 , C07D413/06 , C07D417/10 , C07D487/04 , C07D417/04 , C07D471/04 , A61K31/37
CPC classification number: C07D239/56 , A61K31/352 , A61K31/37 , A61K31/513 , A61K31/5377 , A61K45/06 , C07D401/04 , C07D401/06 , C07D401/10 , C07D403/04 , C07D403/06 , C07D403/10 , C07D403/12 , C07D405/04 , C07D405/06 , C07D405/10 , C07D409/04 , C07D409/10 , C07D413/06 , C07D417/04 , C07D417/10 , C07D471/04 , C07D487/04 , A61K2300/00
Abstract: Myeloperoxidase inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to treat, for example, cardiovascular conditions.
Abstract translation: 髓过氧化物酶抑制剂，含有这些抑制剂的药物组合物以及这些抑制剂用于治疗例如心血管病症的用途。
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公开(公告)号：US08993586B2
公开(公告)日：2015-03-31
申请号：US14497396
申请日：2014-09-26
Applicant: Pfizer Inc.
Inventor： David A. Griffith , Robert L. Dow , Scott W. Bagley , Aaron Smith
IPC: C07D471/20 , A61K31/438
CPC classification number: C07D471/20 , C07D519/00
Abstract: The invention provides a compound of Formula (I) or a pharmaceutically acceptable salt thereof; wherein G is R1, R2 and R3 are as described herein; pharmaceutical compositions thereof; and the use thereof in treating diseases, conditions or disorders modulated by the inhibition of an acetyl-CoA carboxylase enzyme(s) in an animal.
Abstract translation: 本发明提供式（I）化合物或其药学上可接受的盐; 其中G为R 1，R 2和R 3如本文所述; 其药物组合物; 以及其用于治疗通过抑制动物体内的乙酰辅酶A羧化酶调节的疾病，病症或病症的用途。
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公开(公告)号：US20150025098A1
公开(公告)日：2015-01-22
申请号：US14497396
申请日：2014-09-26
Applicant: PFIZER INC.
Inventor： David A. Griffith , Robert L. Dow , Scott W. Bagley , Aaron Smith
IPC: C07D471/20
CPC classification number: C07D471/20 , C07D519/00
Abstract: The invention provides a compound of Formula (I) or a pharmaceutically acceptable salt thereof; wherein G is R1, R2 and R3 are as described herein; pharmaceutical compositions thereof; and the use thereof in treating diseases, conditions or disorders modulated by the inhibition of an acetyl-CoA carboxylase enzyme(s) in an animal.
Abstract translation: 本发明提供式（I）化合物或其药学上可接受的盐; 其中G为R 1，R 2和R 3如本文所述; 其药物组合物; 以及其用于治疗通过抑制动物体内的乙酰辅酶A羧化酶调节的疾病，病症或病症的用途。
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公开(公告)号：US20130296351A1
公开(公告)日：2013-11-07
申请号：US13875604
申请日：2013-05-02
Applicant: Pfizer Inc.
Inventor： Philip A. Carpino , Edward L. Conn , Robert L. Dow , Matthew S. Dowling , David Hepworth , Daniel Wei-Shung Kung , Suvi Orr , Benjamin N. Rocke , Roger B. Ruggeri , Matthew F. Sammons , Joseph S. Warmus , Yan Zhang
IPC: C07D239/56 , A61K45/06 , A61K31/513
CPC classification number: C07D239/56 , A61K31/352 , A61K31/37 , A61K31/513 , A61K31/5377 , A61K45/06 , C07D401/04 , C07D401/06 , C07D401/10 , C07D403/04 , C07D403/06 , C07D403/10 , C07D403/12 , C07D405/04 , C07D405/06 , C07D405/10 , C07D409/04 , C07D409/10 , C07D413/06 , C07D417/04 , C07D417/10 , C07D471/04 , C07D487/04 , A61K2300/00
Abstract: Myeloperoxidase inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to treat, for example, cardiovascular conditions.
Abstract translation: 髓过氧化物酶抑制剂，含有这些抑制剂的药物组合物以及这些抑制剂用于治疗例如心血管病症的用途。
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